Evidence map›Paper›PMID 21916613›Full record

ReviewBiochemistry and cell biology = Biochimie et biologie cellulaire2011

Genomic relationship between SINE retrotransposons, Pol III-Pol II transcription, and chromatin organization: the journey from junk to jewel.

Victoria V Lunyak, Michelle Atallah

Abstract readReview
In one paragraph

Review in Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  9. Article
  10. Epigenetics components of aging in the central nervous system.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2013
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Victoria V LunyakBuck Institute for Age Research, Novato, CA 94945, USA. vlunyak@buckinstitute.org
Michelle Atallah
Buck Institute for Research on Aging · US

Funding

Interdisciplinary Research Consortium in GeroscienceUL1DE019608 · NIDCR · BUCK INSTITUTE FOR RESEARCH ON AGING · PI LITHGOW, GORDON J · 2008 to 2011
$4.0M
NIDCR NIH HHS UL1 DE019608
6 · The paper itself

Abstract

A typical eukaryotic genome harbors a rich variety of repetitive elements. The most abundant are retrotransposons, mobile retroelements that utilize reverse transcriptase and an RNA intermediate to relocate to a new location within the cellular genomes. A vast majority of the repetitive mammalian genome content has originated from the retrotransposition of SINE (100-300 bp short interspersed nuclear elements that are derived from the structural 7SL RNA or tRNA), LINE (7kb long interspersed nuclear element), and LTR (2-3 kb long terminal repeats) transposable element superfamilies. Broadly labeled as "evolutionary junkyard" or "fossils", this enigmatic "dark matter" of the genome possesses many yet to be discovered properties.

Indexed as

GenomeAnimalsChromatinDNA Polymerase IIDNA Polymerase IIIHumansMiceRetroelementsShort Interspersed Nucleotide ElementsChromatinDNA Polymerase IIDNA Polymerase IIIRetroelements

Identifiers

PMID21916613
PMCPMC3660135
OpenAlexW2056694244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.