ReviewRegenerative medicine2011
Developing defined culture systems for human pluripotent stem cells.
Review in Regenerative medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Design of dual peptide-conjugated hydrogels for proliferation and differentiation of human pluripotent stem cells.Materials today. Bio · 2024Article
- Combining the induced pluripotent stem cell (iPSC) technology with chimeric antigen receptor (CAR)-based immunotherapy: recent advances, challenges, and future prospects.Frontiers in cell and developmental biology · 2024Review
- NK Cell Therapeutics for Hematologic Malignancies: from Potential to Fruition.Current hematologic malignancy reports · 2023Review
- CAR-NK as a Rapidly Developed and Efficient Immunotherapeutic Strategy against Cancer.Cancers · 2022Review
- Surface coating materials regulates the attachment and differentiation of mouse embryonic stem cell derived embryoid bodies into mesoderm at culture conditions.Cytotechnology · 2022Article
- Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion.Biomaterials science · 2016Article
- Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Production of human pluripotent stem cell therapeutics under defined xeno-free conditions: progress and challenges.Stem cell reviews and reports · 2015Review
- Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells.Stem cells and cloning : advances and applications · 2015Article
- Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013.Annals of biomedical engineering · 2014Review
- Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stem cells.Stem cell reports · 2014Article
- Efficient generation of functional epithelial and epidermal cells from human pluripotent stem cells under defined conditions.Tissue engineering. Part C, Methods · 2013Article
- Optimized surface markers for the prospective isolation of high-quality hiPSCs using flow cytometry selection.Scientific reports · 2013Article
- Small molecules, big roles -- the chemical manipulation of stem cell fate and somatic cell reprogramming.Journal of cell science · 2012Review
- Derivation and propagation of human embryonic stem cell lines from frozen embryos in an animal product-free environment.Nature protocols · 2012Article
- A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs.Scientific reports · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Human pluripotent stem cells hold promising potential in many therapeutics applications including regenerative medicine and drug discovery. Over the past three decades, embryonic stem cell research has illustrated that embryonic stem cells possess two important and distinct properties: the ability to continuously self-renew and the ability to differentiate into all specialized cell types. In this article, we will discuss the continuing evolution of human pluripotent stem cell culture by examining requirements needed for the maintenance of self-renewal in vitro. We will also elaborate on the future direction of the field toward generating a robust and completely defined culture system, which has brought forth collaborations amongst biologists and engineers. As human pluripotent stem cell research progresses towards identifying solutions for debilitating diseases, it will be critical to establish a defined, reproducible and scalable culture system to meet the requirements of these clinical applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.