Evidence map›Paper›PMID 21915991›Full record

ReviewCytometry. Part A : the journal of the International Society for Analytical Cytology2011

In vivo flow cytometry: a horizon of opportunities.

Valery V Tuchin, Attila Tárnok, Vladimir P Zharov

Abstract readReview
In one paragraph

Review in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
  2. Two-color diffuseJournal of biomedical optics · 2024
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Valery V TuchinResearch-Educational Institute of Optics and Biophotonics, Saratov State University, Saratov 410012, Russia. tuchinvv@mail.ru
Attila Tárnok
Vladimir P Zharov

Funding

In vivo real-time detection of circulating melanoma cellsR01CA131164 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI SUEN, JAMES · 2009 to 2019
$3.1M
Multifunctional nanotubes for in vivo detecting/purging circulating cancer cellsR01EB009230 · NIBIB · UNIV OF ARKANSAS FOR MED SCIS · PI ZHAROV, VLADIMIR P · 2009 to 2012
$1.2M
Photothermal Imaging of Live CellsR01EB000873 · NIBIB · UNIV OF ARKANSAS FOR MED SCIS · PI ZHAROV, VLADIMIR P · 2005 to 2008
$1.1M
In vivo molecular laser detection and treatment of circulating cancer stem cellsR21CA139373 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI ZHAROV, VLADIMIR P · 2009 to 2010
$329k
NCI NIH HHS R01 CA131164NCI NIH HHS R01CA131164NCI NIH HHS R21 CA139373NCI NIH HHS R21CA139373NIBIB NIH HHS R01 EB000873NIBIB NIH HHS R01EB000873NIBIB NIH HHS R01 EB009230NIBIB NIH HHS R01EB009230
6 · The paper itself

Abstract

Flow cytometry (FCM) has been a fundamental tool of biological discovery for many years. Invasive extraction of cells from a living organism, however, may lead to changes in cell properties and prevents studying cells in their native environment. These problems can be overcome by use of in vivo FCM, which provides detection and imaging of circulating normal and abnormal cells directly in blood or lymph flow. The goal of this review is to provide a brief history, features, and challenges of this new generation of FCM methods and instruments. Spectrum of possibilities of in vivo FCM in biological science (e.g., cell metabolism, immune function, or apoptosis) and medical fields (e.g., cancer, infection, and cardiovascular disorder) including integrated photoacoustic-photothermal theranostics of circulating abnormal cells are discussed with focus on recent advances of this new platform.

Indexed as

Flow CytometryMolecular ImagingPhotoacoustic TechniquesAnimalsCardiovascular DiseasesFluorescenceHumansLasersLymphMagnetic Resonance ImagingMiceNanoparticlesNeoplasmsRheologySignal Processing, Computer-AssistedSpectrum Analysis, Raman

Identifiers

PMID21915991
PMCPMC3663136

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.