ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2012
Deep neck infections: a study of 365 cases highlighting recommendations for management and treatment.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
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Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- ESR Essentials: acute infections of the head and neck-practice recommendations by the European Society of Head and Neck Radiology.European radiology · 2026Guideline
- Diagnostic accuracy of contrast-enhanced CT for neck abscesses: A systematic review and meta-analysis of positive predictive value.PloS one · 2022Pooled it
- Segmentation-based morphometric analysis of neck abscesses on MRI: associations with disease severity.European radiology · 2026Article
- Indigenous Status and Outcomes in Deep Neck Space Infections: An ICU Cohort Study.ANZ journal of surgery · 2026Article
- Association of the Modified HALP Score with Disease Complexity in Deep Neck Infections: A Dual-Center Retrospective Study.Diagnostics (Basel, Switzerland) · 2026Article
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- Metagenomic next-generation sequencing-guided management of descending mediastinitis and empyema caused by Segatella baroniae: a case report.BMC pulmonary medicine · 2026Article
- Factors associated with complications among deep neck infections in a community-based hospital in Thailand.BMC infectious diseases · 2026Article
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- Extensive Odontogenic Deep Neck Infection Complicated by Necrotizing Fasciitis and Bilateral Mastitis: A Rare Case Report.Case reports in surgery · 2026Article
- Predictors of systemic complications and prolonged hospitalization in odontogenic infections: a 12-year retrospective analysis of 997 cases.BMC oral health · 2025Article
- Clinical impact of antibiotic resistance in odontogenic infections: a 12-year analysis of 740 cases.Clinical oral investigations · 2025Article
- Comparing vacuum-assisted closure against conventional approach in severe deep neck infection: A retrospective case-control study.World journal of otorhinolaryngology - head and neck surgery · 2025Article
- Predictive factors in difficult postoperative airway management of severe odontogenic deep neck infection.Odontology · 2025Article
- Deep learning detects retropharyngeal edema on MRI in patients with acute neck infections.European radiology experimental · 2025Article
- Application of metagenomic next-generation sequencing in treatment guidance for deep neck space abscess.BMC microbiology · 2025Article
- Management of Deep Neck Infection Associated with Descending Necrotizing Mediastinitis: A Scoping Review.Medicina (Kaunas, Lithuania) · 2025Article
- Risk factors and preventive measures for severe orofacial and neck infections: a three-year observational study.BMC oral health · 2025Observational
10 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims of this investigation were to review the clinical behavior of deep neck infections (DNIs) treated in our institution in order to identify the predisposing factors of life-threatening complications and propose valuable recommendations for management and treatment. A total of 365 adult patients with DNIs were retrospectively identified. One-hundred and thirty-nine patients (38.1%) underwent surgical drainage. Overall, 226 patients (61.9%) responded effectively to intravenous antimicrobial therapy only. There were 67 patients (18.4%) developing life-threatening complications. Diabetes mellitus (odd ratio 5.43; P < 0.001) and multiple deep neck spaces involvement (odd ratio 4.92; P < 0.001) were the strongest independent predictors of complications. The mortality rate was 0.3%. Airway obstruction and descending mediastinitis are the most troublesome complications of DNIs. In selected patients, a trial of intravenous antibiotic therapy associated with an intensive computed tomography-based wait-and-watch policy may avoid an unnecessary surgical procedure. However, about one-fourth of patients present significant comorbidities, which may negatively affect the course of the infection. In these cases and in patients with large or multiple spaces infections, a more aggressive surgical strategy is mandatory.
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