ArticleHeredity2012
Decoupling of differentiation between traits and their underlying genes in response to divergent selection.
Article in Heredity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- When South Meets North: A Joint Contact Zone Coinciding With Environmental Gradients in Three Boreal Tree Species.Molecular ecology · 2026Article
- A combination of stabilizing selection and random walk are associated with phylogenetic signal in hard pines.Annals of botany · 2025Article
- Article
- Population genomic analysis reveals genetic divergence and adaptation inFrontiers in genetics · 2024Article
- Characterization of pollen tube development in distant hybridization of Chinese cork oak (Quercus variabilis L.).Planta · 2023Article
- Antagonistic Effects of Assortative Mating on the Evolution of Phenotypic Plasticity along Environmental Gradients.The American naturalist · 2023Article
- Population differentiation of polygenic score predictions under stabilizing selection.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Interactions between microenvironment, selection and genetic architecture drive multiscale adaptation in a simulation experiment.Journal of evolutionary biology · 2022Article
- The maintenance of standing genetic variation: Gene flow vs. selective neutrality in Atlantic stickleback fish.Molecular ecology · 2022Article
- Genomic Traces of the Fruit FlyInsects · 2021Article
- Genome-wide shifts in climate-related variation underpin responses to selective breeding in a widespread conifer.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Genomics of Clinal Local Adaptation inG3 (Bethesda, Md.) · 2020Article
- Oaks: an evolutionary success story.The New phytologist · 2020Review
- Adaptive introgression as a driver of local adaptation to climate in European white oaks.The New phytologist · 2020Article
- Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish.Nature communications · 2020Article
- Forest genomics: Advancing climate adaptation, forest health, productivity, and conservation.Evolutionary applications · 2020Article
- Assessing the potential for assisted gene flow using past introduction of Norway spruce in southern Sweden: Local adaptation and genetic basis of quantitative traits in trees.Evolutionary applications · 2019Article
- Detecting Adaptive Differentiation in Structured Populations with Genomic Data and Common Gardens.Genetics · 2019Article
- Metapop: An individual-based model for simulating the evolution of tree populations in spatially and temporally heterogeneous landscapes.Molecular ecology resources · 2019Article
- Modularity of genes involved in local adaptation to climate despite physical linkage.Genome biology · 2018Article
Corrections and comments
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
We dissected the relationship between genetic differentiation (Q(ST)) for a trait and its underlying genes (G(STq), differentiation for a quantitative locus) in an evolutionary context, with the aim of identifying the conditions in which these two measurements are decoupled. We used two parameters (θ(B) and θ(W)) scaling the contributions of inter- and intrapopulation allelic covariation between genes controlling the trait of interest. We monitored the changes in θ(B) and θ(W), Q(ST) and G(STq) over successive generations of divergent and stabilizing selection, in simulations for an outcrossing species with extensive gene flow. The dynamics of these parameters are characterized by two phases. Initially, during the earliest generations, differentiation of the trait increases very rapidly and the principal and immediate driver of Q(ST) is θ(B). During subsequent generations, G(STq) increases steadily and makes an equal contribution to Q(ST). These results show that selection first captures beneficial allelic associations at different loci at different populations, and then targets changes in allelic frequencies. The same patterns are observed when environmental change modifies divergent selection, as shown by the very rapid response of θ(B) to the changes of selection regimes. We compare our results with previous experimental findings and consider their relevance to the detection of molecular signatures of natural selection.
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