ReviewJournal of leukocyte biology2011
Tregs and infections: on the potential value of modifying their function.
Review in Journal of leukocyte biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- CD4Nature communications · 2026Article
- Article
- Immune Response Elicited by Recombinant Adenovirus-Delivered Glycoprotein B and Nucleocapsid Protein UL18 and UL25 of HSV-1 in Mice.International journal of molecular sciences · 2024Article
- Mini-Review: Tregs as a Tool for Therapy-Obvious and Non-Obvious Challenges and Solutions.Cells · 2024Review
- Presence of CD80 and Absence of LAT in Modulating Cellular Infiltration and HSV-1 Latency.Viruses · 2024Article
- Regulatory T Cells (Tregs) and COVID-19: Unveiling the Mechanisms, and Therapeutic Potentialities with a Special Focus on Long COVID.Vaccines · 2023Review
- Controlling viral inflammatory lesions by rebalancing immune response patterns.Frontiers in immunology · 2023Review
- Interplay of Regulatory T Cell and Th17 Cells during Infectious Diseases in Humans and Animals.Frontiers in immunology · 2017Review
- Epstein-Barr virus-specific CD8(+) T lymphocytes from diffuse large B cell lymphoma patients are functionally impaired.Clinical and experimental immunology · 2015Article
- Cholera-toxin suppresses carcinogenesis in a mouse model of inflammation-driven sporadic colon cancer.Carcinogenesis · 2015Article
- Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents.PloS one · 2014Article
- Homogeneous expansion of human T-regulatory cells via tumor necrosis factor receptor 2.Scientific reports · 2013Article
- Diet-induced obese mice exhibit altered heterologous immunity during a secondary 2009 pandemic H1N1 infection.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Role of regulatory T cells during virus infection.Immunological reviews · 2013Review
- Galectin-1-mediated suppression of Pseudomonas aeruginosa-induced corneal immunopathology.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- On the role of regulatory T cells during viral-induced inflammatory lesions.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Application of our understanding of pathogenesis of herpetic stromal keratitis for novel therapy.Microbes and infectionReview
- Immune response of T cells during herpes simplex virus type 1 (HSV-1) infection.Journal of Zhejiang University. Science. BReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
CD4(+) T cells, which express a master transcription factor, Foxp3, have been recognized as bona fide Tregs. These cells are essential to maintain immune homeostasis in healthy as well as infected mice and humans. Extensive investigations in the last decade have provided ways to manipulate the Foxp3(+) Treg response therapeutically so the role of such cells in microbe-induced inflammatory reactions can be evaluated. This review focuses on our current understanding of the mechanisms required for the generation and sustenance of Tregs in vivo and the potential value of modulating Tregs to control microbe-induced immunopathological responses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.