Evidence map›Paper›PMID 21914205›Full record

ArticleJournal of biomedical semantics2011

GOMMA: a component-based infrastructure for managing and analyzing life science ontologies and their evolution.

Toralf Kirsten, Anika Gross, Michael Hartung, Erhard Rahm

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Article in Journal of biomedical semantics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Tackling the challenges of matching biomedical ontologies.Journal of biomedical semantics · 2018
    Article
  2. Review
  3. Article
  4. Article
  5. Mining Relation Reversals in the Evolution of SNOMED CT Using MapReduce.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2015
    Article
  6. Article
  7. An effective method of large scale ontology matching.Journal of biomedical semantics · 2014
    Article
  8. Article
  9. Article
  10. A multi-part matching strategy for mapping LOINC with laboratory terminologies.Journal of the American Medical Informatics Association : JAMIA
    Article
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Toralf KirstenInterdisciplinary Centre for Bioinformatics, Universität Leipzig, Härtelstraße 16-18, 04107 Leipzig, Germany. tkirsten@izbi.uni-leipzig.de.
Anika Gross
Michael Hartung
Erhard Rahm

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOntologies are increasingly used to structure and semantically describe entities of domains, such as genes and proteins in life sciences. Their increasing size and the high frequency of updates resulting in a large set of ontology versions necessitates efficient management and analysis of this data.

resultsWe present GOMMA, a generic infrastructure for managing and analyzing life science ontologies and their evolution. GOMMA utilizes a generic repository to uniformly and efficiently manage ontology versions and different kinds of mappings. Furthermore, it provides components for ontology matching, and determining evolutionary ontology changes. These components are used by analysis tools, such as the Ontology Evolution Explorer (OnEX) and the detection of unstable ontology regions. We introduce the component-based infrastructure and show analysis results for selected components and life science applications. GOMMA is available at http://dbs.uni-leipzig.de/GOMMA.

conclusionsGOMMA provides a comprehensive and scalable infrastructure to manage large life science ontologies and analyze their evolution. Key functions include a generic storage of ontology versions and mappings, support for ontology matching and determining ontology changes. The supported features for analyzing ontology changes are helpful to assess their impact on ontology-dependent applications such as for term enrichment. GOMMA complements OnEX by providing functionalities to manage various versions of mappings between two ontologies and allows combining different match approaches.

Identifiers

PMID21914205
PMCPMC3198872

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.