Evidence map›Paper›PMID 21913066›Full record

ReviewClinical reviews in allergy & immunology2011

Cutting-edge issues in autoimmune uveitis.

Roger A Levy, Francisco Assis de Andrade, Ivan Foeldvari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Uveitis associated with juvenile idiopathic arthritis.Nature reviews. Rheumatology · 2015
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roger A LevyDisciplina de Reumatologia, térreo, Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Federico Foundation, Rio de Janeiro, Brazil. Roger.a.levy@gmail.com
Francisco Assis de Andrade
Ivan Foeldvari

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune uveitis (AIU) is among the leading causes of preventable blindness. It can be isolated, precede, or appear in the course of a systemic autoimmune inflammatory disease. When suspected, AIU should be promptly referred to an ophthalmologist for proper anatomic classification and local treatment. In recurrent and chronic forms, systemic treatment should be started, usually with corticosteroids and immunesuppressors. In cases of lack of efficacy or intolerance, biologic agents such as monoclonal antibodies anti-TNF (infliximab and adalimumab) and others (abatacept and tocilizumab) are being used. The clinical diseases associated to AIU and the experimental models have helped in the understanding of the pathogenic mechanism. The treatment schemes have improved, and recent advances in basic knowledge are leading to even more effective targeted therapies.

Indexed as

ImmunotherapyAbataceptAdrenal Cortex HormonesAnimalsAntibodies, MonoclonalAutoimmune DiseasesDiagnosis, DifferentialHumansImmunoconjugatesImmunosuppressive AgentsInterleukin-6Models, AnimalMolecular Targeted TherapyTumor Necrosis Factor-alphaUveitisAbataceptAdrenal Cortex HormonesAntibodies, MonoclonalImmunoconjugatesImmunosuppressive AgentsInterleukin-6TNF protein, humanTumor Necrosis Factor-alpha

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.