Evidence map›Paper›PMID 21913059›Full record

ArticleEuropean radiology2012

Severity assessment of pulmonary embolism using dual energy CT - correlation of a pulmonary perfusion defect score with clinical and morphological parameters of blood oxygenation and right ventricular failure.

Sven F Thieme, Nima Ashoori, Fabian Bamberg, Wieland H Sommer, Thorsten R C Johnson, Hanno Leuchte, Alexander Becker, Daniel Maxien, Andreas D Helck, Jürgen Behr and 2 more

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Article in European radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Dual-energy CT in pulmonary vascular disease.The British journal of radiology · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Acute pulmonary embolism multimodality imaging prior to endovascular therapy.The international journal of cardiovascular imaging · 2021
    Review
  13. Article
  14. Article
  15. Pulmonary arteries: imaging of pulmonary embolism and beyond.Cardiovascular diagnosis and therapy · 2019
    Review
  16. State of the art: utility of multi-energy CT in the evaluation of pulmonary vasculature.The international journal of cardiovascular imaging · 2019
    Review
  17. Article
  18. Article
  19. Clinical and echocardiographic findings of patients with suspected acute pulmonary thromboembolism who underwent computed tomography pulmonary angiography.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sven F ThiemeDepartment of Clinical Radiology, Ludwig-Maximilians-Universität, Klinikum Großhadern, Marchioninistr.15, 81377 München, Germany. sven.thieme@med.uni-muenchen.de
Nima Ashoori
Fabian Bamberg
Wieland H Sommer
Thorsten R C Johnson
Hanno Leuchte
Alexander Becker
Daniel Maxien
Andreas D Helck
Jürgen Behr
Maximilian F Reiser
Konstantin Nikolaou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo correlate a Dual Energy (DE)-based visual perfusion defect scoring system with established CT-based and clinical parameters of pulmonary embolism (PE) severity.

methodsIn 63 PE patients, DE perfusion maps were visually scored for perfusion defects (P-score). Vascular obstruction was quantified using the Mastora score. Both scores were correlated with short-axis diameters of the right and left ventricle, their ratio (RV/LV ratio), width of the pulmonary trunk, a number of clinical parameters and each other. Univariate and multivariate analyses were performed. Times to generate both scores were recorded.

resultsAfter univariate and multivariate analysis, a significant (p < 0.05) correlation with the P-score was shown for the Mastora score (r = 0.65), RV/LV ratio (r = 0.47), width of the pulmonary trunk (r = 0.26), troponin I (r = 0.43) and PaO(2) (r = -0.50). For the left ventricular diameter, only univariate analysis showed a significant correlation. Mastora score correlated significantly with RV/LV ratio (r = 0.36), width of the pulmonary trunk (r = 0.27), PaO(2) (r = -0.41) and troponin I (r = 0.37). Mean time for generating the P-score was significantly shorter than for the Mastora score.

conclusionsA DE-based P-score correlates with a number of parameters of PE severity. It might be easier and faster to perform than some traditional CT scoring methods for vascular obstruction.

Indexed as

AgedBloodCardiologyContrast MediaFemaleHumansIohexolLungMaleMiddle AgedOxygenPerfusionPulmonary EmbolismTomography, X-Ray ComputedVentricular Dysfunction, RightContrast MediaIohexoliopromideOxygen

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.