ReviewReviews in endocrine & metabolic disorders2011
Effects of polymorphisms in gonadotropin and gonadotropin receptor genes on reproductive function.
Review in Reviews in endocrine & metabolic disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Trial
- Genetics of infertility and "assisted fertilization" in the Bible: The case of Abraham and his family.Andrology · 2026Review
- A point-of-care assay for genotyping women prior to ovarian stimulation with recombinant or human menopausal gonadotropins in assisted reproduction.Frontiers in endocrinology · 2026Article
- High serum FSH levels on day 7 of stimulation are negatively associated with oocyte retrieval in GnRH antagonist protocols: real-world evidence from 9,969 IVF cycles in China.Frontiers in endocrinology · 2026Article
- The impact of genetic variants in folliculogenesis and steroidogenesis pathways on ovarian response: a post hoc multicenter multiethnic cohort study.Journal of assisted reproduction and genetics · 2025Article
- Unexpected hypo-responders in in vitro fertilization: The impact of higher gonadotropin doses on oocyte yield.Turkish journal of obstetrics and gynecology · 2025Article
- Article
- The serum follicle stimulating hormone-to-luteinizing hormone ratios can predict assisted reproductive technology outcomes in women undergoing gonadotropin releasing hormone antagonist protocol.Frontiers in endocrinology · 2023Article
- Protein kinase A drives paracrine crisis and WNT4-dependent testis tumor in Carney complex.The Journal of clinical investigation · 2021Article
- An overview of FSH-FSHR biology and explaining the existing conundrums.Journal of ovarian research · 2021Review
- Reduced FSH and LH action: implications for medically assisted reproduction.Human reproduction (Oxford, England) · 2021Review
- Recent advances in understanding gonadotropin signaling.Faculty reviews · 2021Review
- The Relationship Between Serum Delta FSH Level and Ovarian Response in IVF/ICSI Cycles.Frontiers in endocrinology · 2020Article
- An Observational Retrospective Cohort Trial on 4,828 IVF Cycles Evaluating Different Low Prognosis Patients Following the POSEIDON Criteria.Frontiers in endocrinology · 2019Article
- Frequency of the T307A, N680S, and -29G>A single-nucleotide polymorphisms in the follicle-stimulating hormone receptor in Mexican subjects of Hispanic ancestry.Reproductive biology and endocrinology : RB&E · 2018Article
- Human Chorionic Gonadotropin and Breast Cancer.International journal of molecular sciences · 2017Review
- The Common Follicle-Stimulating Hormone Receptor (FSHR) Promoter Polymorphism FSHR -29G > A Affects Androgen Production in Normal Human Small Antral Follicles.Frontiers in endocrinology · 2017Article
- Follicle-stimulating hormone regulates expression and activity of epidermal growth factor receptor in the murine ovarian follicle.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Genotyping common FSHR polymorphisms based on competitive amplification of differentially melting amplicons (CADMA).Journal of assisted reproduction and genetics · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gonadotropins, the action of which is mediated at the level of their gonadal receptors, play a key role in sexual development, reproductive functions and in metabolism. The involvement of the gonadotropins and their receptor genotypes on reproductive function are widely studied. A large number of gonadotropins and their receptors gene polymorphisms are known, but the only one considerable as a clear, absolute genetic marker of reproductive features or disfunctions is the FSHR Asn680Ser polymorphism, since it modulates ovarian response to FSH. The aim of these studies would to be the prediction of the genetic causes of sex-related diseases to enable a customized clinical setting based on individual response of patients undergoing gonadotropin stimulation. In this review we discuss the latest information about the effects of polymorphisms of the gonadotropins and their receptor genes on reproductive functions of both male and female, and discuss their patho-physiological implications.
Indexed as
Identifiers
21912887What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.