ReviewInternational journal of colorectal disease2012
The management of primary small bowel and colon lymphoma--a review.
Review in International journal of colorectal disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Surgery plus chemotherapy versus chemotherapy alone in primary intestinal lymphoma: a meta-analysis.The Journal of international medical research · 2021Pooled it
- Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016Pooled it
- Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies.European journal of haematology · 2026Review
- The Role of Surgery in the Management of Intestinal Diffuse Large B-Cell Lymphoma (DLBCL): A Propensity Score-Matched Analysis.Annals of surgical oncology · 2026Article
- Management of complicated primary intestinal lymphoma in the emergency setting. Experience at quaternary hospital.Langenbeck's archives of surgery · 2025Observational
- Rare primary colonic T cell lymphoma with curative resection by endoscopic submucosal dissection: A case report.World journal of clinical cases · 2024Article
- Computed tomography-based radiomics combined with machine learning allows differentiation between primary intestinal lymphoma and Crohn's disease.World journal of gastroenterology · 2024Article
- Nomogram based on computed tomography images and clinical data for distinguishing between primary intestinal lymphoma and Crohn's disease: a retrospective multicenter study.Frontiers in medicine · 2023Article
- Clinical and endoscopic features of primary small bowel lymphoma: a single-center experience from mainland China.Frontiers in oncology · 2023Article
- Unusual presentation of aggressive high-grade B-cell lymphoma of colonic origin: A case report and review of the literature.Clinical case reports · 2022Article
- Rare Jejunal Large B-cell Lymphoma Mimicking a Crohn's Disease Without Terminal Ileum Involvement.Cureus · 2022Article
- Surgery shows survival benefit in patients with primary intestinal diffuse large B-cell lymphoma: A population-based study.Cancer medicine · 2021Article
- Surgical Management of Small Bowel Lymphoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- How we treat mature B-cell neoplasms (indolent B-cell lymphomas).Journal of hematology & oncology · 2021Review
- Overview of microRNAs as liquid biopsy biomarkers for colorectal cancer sub-type profiling and chemoresistance.Cancer drug resistance (Alhambra, Calif.) · 2021Review
- Article
- Synchronous diffuse large B-cell lymphoma of the small intestine and adenocarcinoma of the colon.The Korean journal of internal medicine · 2018Article
- Management of Primary Gastrointestinal Non-Hodgkin Lymphomas: a Population-Based Survival Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016Article
- Radiological Features of Gastrointestinal Lymphoma.Gastroenterology research and practice · 2016Review
- Primary colonic lymphoma: An incidental finding in a patient with a gallstone attack.World journal of clinical cases · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe management of primary small bowel and colon lymphoma is controversial. A review of the literature was therefore undertaken to evaluate the evidence for the classification, staging, diagnosis, and treatment of primary small bowel and colon lymphoma and guide management.
methodsA literature search was performed utilising Embase, Medline, and Pubmed and papers were evaluated on an individual basis.
resultsConsensus opinion favours the WHO classification scheme and the TNM staging systems for primary small bowel and colon lymphoma. CT enteroclysis and barium enterolysis are recommended for the diagnosis of primary small bowel lymphoma and capsule endoscopy and double-balloon enteroscopy maybe useful diagnostic tools. In terms of the diagnosis and staging of primary colonic lymphoma, the evidence is scarce and CT is to be recommended. The mainstay of treatment for primary GI lymphoma is surgery and/or chemotherapy. For primary small bowel and colonic lymphoma, there was no definitive evidence regarding the benefits of either strategy; however, chemotherapy seemed to give a survival benefit over surgery alone for primary small bowel lymphoma and colonic lymphoma was skewed towards surgery plus chemotherapy due to the large number of patients presenting as an emergency.
conclusionPublished data regarding the management of primary small bowel and colon lymphoma is very limited. Classification and staging should be standardised to enable accurate evaluation of investigations and treatments and a large RCT undertaken to compare chemotherapy and surgery. Currently, we would recommend that management should involve chemotherapy with surgery reserved for those with clinical indication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.