Evidence map›Paper›PMID 21912461›Full record

ArticleWorld journal of gastroenterology2011

Cure of alopecia areata after eradication of Helicobacter pylori: a new association?

Germán Campuzano-Maya

Abstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

  1. Cutaneous and Gut Dysbiosis in Alopecia Areata: A Review.JID innovations : skin science from molecules to population health · 2025
    Review
  2. Article
  3. Selected Markers of Inflammation in the Saliva of Children Infected withInternational journal of molecular sciences · 2024
    Article
  4. Pivotal role ofFrontiers in medicine · 2024
    Review
  5. Alopecia Areata Barbae in a Nutshell.Skin appendage disorders · 2023
    Review
  6. Review
  7. Article
  8. Evaluating the relationship betweenAnnals of medicine and surgery (2012) · 2021
    Article
  9. Relationship BetweenInternational journal of general medicine · 2021
    Review
  10. Article
  11. Association betweenMiddle East journal of digestive diseases · 2017
    Article
  12. New aspects of the treatment of alopecia areata.Postepy dermatologii i alergologii · 2014
    Review
  13. Review
  14. Helicobacter pylori and skin autoimmune diseases.World journal of gastroenterology · 2014
    Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Germán Campuzano-MayaFaculty of Medicine, University of Antioquia. Medical Director, Laboratorio Clínico Hematológico, Carrera 43C No. 5-33, Medellín, Colombia. gcm@lch.co
Universidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alopecia areata is a disease of the hair follicles, with strong evidence supporting autoimmune etiology. Alopecia areata is frequently associated with immune-mediated diseases with skin manifestations such as psoriasis and lichen planus, or without skin manifestations such as autoimmune thyroiditis and idiopathic thrombocytopenic purpura. Helicobacter pylori (H. pylori) infection is present in around 50% of the world's population and has been associated with a variety of immune-mediated extra-digestive disorders including autoimmune thyroiditis, idiopathic thrombocytopenic purpura, and psoriasis. A case of a 43-year old man with an 8-mo history of alopecia areata of the scalp and beard is presented. The patient was being treated by a dermatologist and had psychiatric support, without any improvement. He had a history of dyspepsia and the urea breath test confirmed H. pylori infection. The patient went into remission from alopecia areata after H. pylori eradication. If such an association is confirmed by epidemiological studies designed for this purpose, new therapeutic options could be available for these patients, especially in areas where infection with H. pylori is highly prevalent.

Indexed as

AdultAlopecia AreataAmoxicillinAnti-Bacterial AgentsBreath TestsClarithromycinDyspepsiaEnzyme InhibitorsHelicobacter InfectionsHelicobacter pyloriHumansMaleOmeprazoleAmoxicillinAnti-Bacterial AgentsClarithromycinEnzyme InhibitorsOmeprazoleAlopecia areataEradication treatmentHelicobacter pyloriMolecular mimicry

Identifiers

PMID21912461
PMCPMC3158418
OpenAlexW2117541057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.