SynthesisWorld journal of gastroenterology2011
Hemihepatic versus total hepatic inflow occlusion during hepatectomy: a systematic review and meta-analysis.
Synthesis in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The E-AHPBA-ESSO-Innsbruck consensus recommendations on peri- and postoperative management following liver resection.The British journal of surgery · 2025Guideline
- Meta-analysis of the effect of the pringle maneuver on long-term oncological outcomes following liver resection.Scientific reports · 2021Pooled it
- Systematic review of pathophysiological changes following hepatic resection.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2014Pooled it
- Effect of milrinone-terlipressin infusion on blood loss and portal pressure during hepatic resection: a randomized controlled trial.Anesthesia and pain medicine · 2026Article
- Efficiency and safety of laparoscopic left hemihepatectomy: A study of intrathecalWorld journal of gastrointestinal surgery · 2024Article
- Comparison of the benefits and risks of hemihepatic inflow occlusion: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Inflow control can be safely used in laparoscopic subsegmentectomy of the liver: a single-center 10-year experience.BMC surgery · 2023Article
- Review
- The effect of the number of hepatic inflow occlusion times on the prognosis of ruptured hepatocellular carcinoma patients after hepatectomy.BMC surgery · 2022Article
- Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study.World journal of hepatology · 2019Article
- Regional Ischemic Preconditioning Has Clinical Value in Cirrhotic HCC Through MAPK Pathways.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- Differential Effects of Three Techniques for Hepatic Vascular Exclusion during Resection for Liver Cirrhosis on Hepatic Ischemia-Reperfusion Injury in Rats.Gastroenterology research and practice · 2018Article
- Management of centrally located hepatocellular carcinoma: Update 2016.World journal of hepatology · 2017Review
- Outcome using selective hemihepatic vascular occlusion and Pringle maneuver for hepatic resection of liver cavernous hemangioma.World journal of surgical oncology · 2015Article
- Anatomic resection of liver segments 6-8 for hepatocellular carcinoma.World journal of gastroenterology · 2014Article
- Central hepatectomy under sequential hemihepatic control.Langenbeck's archives of surgery · 2012Article
- d-Pinitol protects against endoplasmic reticulum stress and apoptosis in hepatic ischemia-reperfusion injury via modulation of AFT4-CHOP/GRP78 and caspase-3 signaling pathways.International journal of immunopathology and pharmacologyArticle
- Central bisegmentectomy for malignant liver tumors: experience in 8 patients.International surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the clinical outcomes of patients undergoing hepatectomy with hemihepatic vascular occlusion (HHO) compared with total hepatic inflow occlusion (THO).
methodsRandomized controlled trials (RCTs) comparing hemihepatic vascular occlusion and total hepatic inflow occlusion were included by a systematic literature search. Two authors independently assessed the trials for inclusion and extracted the data. A meta-analysis was conducted to estimate blood loss, transfusion requirement, and liver injury based on the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Either the fixed effects model or random effects model was used.
resultsFour RCTs including 338 patients met the predefined inclusion criteria. A total of 167 patients were treated with THO and 171 with HHO. Meta-analysis of AST levels on postoperative day 1 indicated higher levels in the THO group with weighted mean difference (WMD) 342.27; 95% confidence intervals (CI) 217.28-467.26; P = 0.00 001; I(2) = 16%. Meta-analysis showed no significant difference between THO group and HHO group on blood loss, transfusion requirement, mortality, morbidity, operating time, ischemic duration, hospital stay, ALT levels on postoperative day 1, 3 and 7 and AST levels on postoperative day 3 and 7.
conclusionHemihepatic vascular occlusion does not offer satisfying benefit to the patients undergoing hepatic resection. However, they have less liver injury after liver resections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.