ReviewNature reviews. Neurology2011
Diagnosis and treatment of neurocysticercosis.
Review in Nature reviews. Neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02233855 (NACC 002), which is not on this map. Cited by 117 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NACC 002: A Multicenter Prospective Natural History Study of Patients Presenting With Neurocysticercosis in North America
Who cites it
117 citing papers in PubMed, 3 syntheses or guidelines pooled it, 244 citations in OpenAlex.
- Treatment outcome in patients with spinal neurocysticercosis: a systematic review of published cases and case series.Future microbiology · 2025Pooled it
- Diagnosis and Treatment of Neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Diagnosis and Treatment of Neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH).The American journal of tropical medicine and hygiene · 2018Guideline
- Distinguishing neurocysticercosis epilepsy from epilepsy of unknown etiology using a minimal serum mass profiling platform.Experimental parasitology · 2018Trial
- Enhanced steroid dosing reduces seizures during antiparasitic treatment for cysticercosis and early after.Epilepsia · 2014Trial
- PET reveals inflammation around calcified Taenia solium granulomas with perilesional edema.PloS one · 2013Trial
- Cysticercosis and neurocysticercosis in Eastern Zambia: A cross-sectional, community-based study.IJID regions · 2026Article
- Three decades of neurocysticercosis mandatory notification in a Brazilian endemic region: clinical evolution and severity patterns.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- PCR-Confirmed Convexity Subarachnoid Neurocysticercosis with Negative Serology: A Case Report.Pathogens (Basel, Switzerland) · 2026Article
- Vanishing brain space-occupying lesion in a child: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Neurocysticercosis by Taenia sp. in a female alpaca (Vicugna pacos) from Germany.BMC veterinary research · 2026Article
- Multifocal streptococcus intermedius abscess mimicking neurocysticercosis clinical and radiological findings: A case report and literature review.Radiology case reports · 2026Article
- Article
- Solitary neurocysticercosis mimicking tuberculoma and glioblastoma: A diagnostic challenge in a low-resource setting.Surgical neurology international · 2026Article
- Article
- Identification of abnormal patterns of evolution of neurocysticercosis cysts and what they might indicate.medRxiv : the preprint server for health sciences · 2025Article
- Echoes of Dormancy: Anomic Aphasia Unveils Neurocysticercosis Reactivation in a Patient on Semaglutide.NeuroSci · 2025Article
- The hidden threat of cysticercosis: A neglected public health problem.Open veterinary journal · 2025Review
- Racemose Neurocysticercosis Presenting As Vasculitic Infarct and Obstructive Hydrocephalus: A Rare Presentation.Cureus · 2025Article
- Ivermectin as a promising therapeutic option for onchocerciasis-associated epilepsy.Epilepsia open · 2025Review
57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Neurocysticercosis is a parasitic disease caused by the larval (cystic) form of the pork cestode tapeworm, Taenia solium, and is a major cause of acquired seizures and epilepsy worldwide. Development of sensitive and specific diagnostic methods, particularly CT and MRI, has revolutionized our knowledge of the burden of cysticercosis infection and disease, and has led to the development of effective antihelminthic treatments for neurocysticercosis. The importance of calcified granulomas with perilesional edema as foci of seizures and epilepsy in populations where neurocysticercosis is endemic is newly recognized, and indicates that treatment with anti-inflammatory agents could have a role in controlling or preventing epilepsy in these patients. Importantly, neurocysticercosis is one of the few diseases that could potentially be controlled or eliminated-an accomplishment that would prevent millions of cases of epilepsy. This Review examines the rationale for treatment of neurocysticercosis and highlights the essential role of inflammation in the pathogenesis of disease, the exacerbation of symptoms that occurs as a result of antihelminthic treatment, and the limitations of current antihelminthic and anti-inflammatory treatments.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.