Evidence map›Paper›PMID 21911565›Full record

ArticleAntimicrobial agents and chemotherapy2011

Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea.

Kyungwon Lee, Jong Hwa Yum, Dongeun Yong, Seok Hoon Jeong, Gian Maria Rossolini, Jean-Denis Docquier, Yunsop Chong

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kyungwon LeeDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea.
Jong Hwa Yum
Dongeun Yong
Seok Hoon Jeong
Gian Maria Rossolini
Jean-Denis Docquier
Yunsop Chong
Yonsei University · KRUniversity of Siena · ITDong-Eui University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.

Indexed as

Amino Acid SubstitutionAdolescentAnti-Bacterial Agentsbeta-Lactamasesbeta-Lactam ResistanceCefotaximeCeftazidimeClavulanic AcidConjugation, GeneticEscherichia coliFemaleHumansKineticsKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-Lactamasesbeta-lactamase TEM-43CefotaximeCeftazidimeClavulanic Acid

Identifiers

PMID21911565
PMCPMC3232759
OpenAlexW1969664154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.