ArticleMethods in molecular biology (Clifton, N.J.)2012
Analysis of chemotaxis in Dictyostelium.
Article in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Cross-Species Applications of Peptide Substrate Reporters to Quantitative Measurements of Kinase Activity.ACS measurement science au · 2024Article
- Leep2A and Leep2B function as a RasGAP complex to regulate macropinosome formation.The Journal of cell biology · 2024Article
- Trade-offs in concentration sensing in dynamic environments.Biophysical journal · 2024Article
- Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration.Nature cell biology · 2022Article
- Proteomic and Transcriptomic Profiling Identifies Early Developmentally Regulated Proteins inCells · 2019Article
- Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation.Nature communications · 2018Article
- Decoding the chemotactic signal.Journal of leukocyte biology · 2018Review
- Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation.Journal of visualized experiments : JoVE · 2017Article
- The novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cells.Molecular biology of the cell · 2016Article
- A new class of cancer-associated PTEN mutations defined by membrane translocation defects.Oncogene · 2015Article
- Engineering PTEN function: membrane association and activity.Methods (San Diego, Calif.) · 2015Article
- Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.Oncogene · 2014Article
- Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.Nature communications · 2014Article
- Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer.Science (New York, N.Y.) · 2014Article
- Identification of a farnesol analog as a Ras function inhibitor using both an in vivo Ras activation sensor and a phenotypic screening approach.Molecular and cellular biochemistry · 2014Article
- Rho GTPases orient directional sensing in chemotaxis.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Multiscale mechanisms of cell migration during development: theory and experiment.Development (Cambridge, England) · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Dictyostelium discoideum is an excellent model organism for the study of directed cell migration, since Dictyostelium cells show robust chemotactic responses to the chemoattractant cAMP. Many powerful experimental tools are applicable, including forward and reverse genetics, biochemistry, microscopy, and proteomics. Recent studies have demonstrated that many components involved in chemotaxis are functionally conserved between human neutrophils and Dictyostelium amoebae. In this chapter, we describe how to define the functions of proteins that mediate and regulate cell motility, cell polarity, and directional sensing during chemotaxis in Dictyostelium.
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Registered trials
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