ArticleFolia microbiologica2011
Emergence of Aureobasidium pullulans as human fungal pathogen and molecular assay for future medical diagnosis.
Article in Folia microbiologica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- First case ofMedical mycology case reports · 2025Article
- Introducing two new genera,Fungal systematics and evolution · 2025Article
- Genome mining the black-yeast Aureobasidium pullulans NRRL 62031 for biotechnological traits.BMC genomics · 2025Article
- The impact of Aureobasidium melanogenum cells and extracellular vesicles on human cell lines.Scientific reports · 2025Article
- Yeasts Inhabiting Extreme Environments and Their Biotechnological Applications.Microorganisms · 2022Review
- Mycobiomes of the Ocular Surface in Bacterial Keratitis Patients.Frontiers in ophthalmology · 2022Article
- Virulence Traits and Population Genomics of the Black YeastJournal of fungi (Basel, Switzerland) · 2021Article
- Modified Rhodopsins FromFrontiers in molecular biosciences · 2021Article
- Phenotypes Associated with Pathogenicity: Their Expression in Arctic Fungal Isolates.Microorganisms · 2019Article
- Article
- Molecular Identification of a Moricin Family Antimicrobial Peptide (Px-Mor) FromFrontiers in microbiology · 2019Article
- Inherited CARD9 Deficiency: Invasive Disease Caused by Ascomycete Fungi in Previously Healthy Children and Adults.Journal of clinical immunology · 2018Review
- Fungi in perennial ice from Scărișoara Ice Cave (Romania).Scientific reports · 2018Article
- The current status of Aureobasidium pullulans in biotechnology.Folia microbiologica · 2018Review
- Diversity of Yeasts and Molds by Culture-Dependent and Culture-Independent Methods for Mycobiome Surveillance of Traditionally Prepared Dried Starters for the Production of Indian Alcoholic Beverages.Frontiers in microbiology · 2018Article
- Cultivable Microbial Diversity Associated With Cellular Phones.Frontiers in microbiology · 2018Article
- Article
- Spontaneous circadian rhythms in a cold-adapted natural isolate of Aureobasidium pullulans.Scientific reports · 2017Article
- Successful treatment ofIDCases · 2017Article
- Genome sequencing of four Aureobasidium pullulans varieties: biotechnological potential, stress tolerance, and description of new species.BMC genomics · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the great importance of Aureobasidium pullulans in biotechnology, the fungus had emerged as an opportunistic human pathogen, especially among immunocompromised patients. Clinical detection of this rare human fungal pathogen presently relies on morphology diagnosis which may be misleading. Thus, a sensitive and accurate quantitative molecular assay for A. pullulans remains lacking. In this study, we presented the microscopy observations of A. pullulans that reveals the phenotypic plasticity of the fungus. A. pullulans-specific primers and molecular beacon probes were designed based on the fungal 18S ribosomal RNA (rRNA) gene. Comparison of two probes with varied quencher chemistry, namely BHQ-1 and Tamra, revealed high amplification efficiency of 104% and 108%, respectively. The optimized quantitative real-time PCR (qPCR) assays could detect and quantify up to 1 pg concentration of A. pullulans DNA. Both assays displayed satisfactory performance parameters at fast thermal cycling mode. The molecular assay has great potential as a molecular diagnosis tool for early detection of fungal infection caused by A. pullulans, which merits future study in clinical diagnosis.
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Registered trials
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