ReviewHeart failure reviews2012
Animal models of cardiorenal syndrome: a review.
Review in Heart failure reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review).International journal of molecular medicine · 2026Review
- A novel mouse model of adenine-supplemented high-fat diet induced cardiovascular-kidney-metabolic syndrome.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- A new animal model of cardiorenal syndrome could be established by inducing heart failure through coronary artery ligation in spontaneously hypertensive rats.Scientific reports · 2024Article
- Risk of mortality associated to chronic kidney disease in patients with complete left bundle branch block.Scientific reports · 2024Article
- Incident heart failure and the subsequent risk of progression to end stage kidney disease in individuals with type 2 diabetes.Cardiovascular diabetology · 2024Article
- The association of plasma NT-proBNP level and progression of diabetic kidney disease.Renal failure · 2023Article
- Pericyte detachment and renal congestion involve interstitial injury and fibrosis in Dahl salt-sensitive rats and humans with heart failure.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Metabolomics Assessment of Volume Overload-Induced Heart Failure and Oxidative Stress in the Kidney.Metabolites · 2023Article
- Cardionephrology from the point of view of the cardiologist: no more agree to disagree-getting to 'yes' for every patient.Clinical kidney journal · 2021Article
- Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model.Frontiers in pharmacology · 2021Article
- Article
- Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome.Journal of the American Society of Nephrology : JASN · 2020Observational
- Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction.Cardiology research and practice · 2020Article
- Current animal models for the study of congestion in heart failure: an overview.Heart failure reviews · 2019Review
- N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy.Scientific reports · 2017Article
- Effect of Gamma-Oryzanol as Therapeutic Agent to Prevent Cardiorenal Metabolic Syndrome in Animals Submitted to High Sugar-Fat Diet.Nutrients · 2017Article
- Aging Male Spontaneously Hypertensive Rat as an Animal Model for the Evaluation of the Interplay between Contrast-Induced Acute Kidney Injury and Cardiorenal Syndrome in Humans.Cardiorenal medicine · 2016Review
- Characterization of a murine model of cardiorenal syndrome type 1 by high-resolution Doppler sonography.Journal of ultrasound · 2015Article
- Animal Models to Study Links between Cardiovascular Disease and Renal Failure and Their Relevance to Human Pathology.Frontiers in immunology · 2015Review
- Imaging of cardiac and renal perfusion in a rat model with 13N-NH 3 micro-PET.The international journal of cardiovascular imaging · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of heart failure and renal failure is increasing and is associated with poor prognosis. Moreover, these conditions do often coexist and this coexistence results in worsened outcome. Various mechanisms have been proposed as an explanation of this interrelation, including changes in hemodynamics, endothelial dysfunction, inflammation, activation of renin-angiotensin-aldosterone system, and/or sympathetic nervous system. However, the exact mechanisms initializing and maintaining this interaction are still unknown. In many experimental studies on cardiac or renal dysfunction, the function of the other organ was either not addressed or the authors failed to show any decline in its function despite histological changes. There are few studies in which the dysfunction of both heart and kidney function has been described. In this review, we discuss animal models of combined cardiorenal dysfunction. We show that translation of the results from animal studies is limited, and there is a need for new and better models of the cardiorenal interaction to improve our understanding of this syndrome. Finally, we propose several requirements that a new animal model should meet to serve as a tool for studies on the cardiorenal syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.