Evidence map›Paper›PMID 21909806›Full record

ArticleHeart and vessels2012

Aspirin, clopidogrel, and warfarin use and outcomes in a cohort of 580 patients discharged after hospitalization for decompensated heart failure.

Güliz Kozdağ, Mehmet Yaymacı, Gökhan Ertaş, Umut Celikyurt, Tayfun Sahin, Teoman Kılıç, Dilek Ural

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Antithrombotics in heart failure.Croatian medical journal · 2014
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Güliz KozdağDepartment of Cardiology, Faculty of Medicine, Kocaeli University, Gümüşhane, Turkey.
Mehmet Yaymacı
Gökhan Ertaş
Umut Celikyurt
Tayfun Sahin
Teoman Kılıç
Dilek Ural
Kocaeli Üniversitesi · TRGümüşhane University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The benefits of taking of aspirin, clopidogrel, and warfarin in relation to cardiovascular mortality and re-hospitalization in chronic heart failure (HF) patients have been called into question. We examined the outcomes (cardiac mortality and/or HF re-hospitalization) in patients discharged from our hospital between January 2003 and July 2009 after hospitalization for chronic decompensated HF. Of 580 HF patients (mean age, 63 ± 13 years; mean ejection fraction, 26 ± 9%, 63% with coronary disease and 37% without coronary disease), 207 patients (36%) died due to cardiovascular reasons, and 313 (54%) required HF re-hospitalization for decompensated HF during a 39 ± 14 month follow-up period. 101 (17%) patients were taking clopidogrel during enrollment in the study. When comparing patients who were on clopidogrel treatment with those who were not, clopidogrel was found to have a beneficial effect on cardiac mortality (27 vs. 38%, P = 0.04). In conclusion, in this observational prospective study, patients who used clopidogrel showed decreased cardiac mortality [HR, 0.566 (95% CI 0.332-0.964), P = 0.036] compared to patients who did not take clopidogrel. Clopidogrel had a beneficial effect on the survival of chronic HF patients in the long term.

Indexed as

Patient DischargePractice Patterns, Physicians'AgedAngiotensin-Converting Enzyme InhibitorsAnticoagulantsAspirinChi-Square DistributionChronic DiseaseClopidogrelDrug InteractionsDrug UtilizationFemaleHealth Care SurveysHeart FailureHumansMaleAngiotensin-Converting Enzyme InhibitorsAnticoagulantsAspirinClopidogrelPlatelet Aggregation InhibitorsTiclopidineWarfarin

Identifiers

PMID21909806
OpenAlexW2092606616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.