ArticleJournal of materials science. Materials in medicine2011
Hydroxyapatite coating on magnesium with MgF₂ interlayer for enhanced corrosion resistance and biocompatibility.
Article in Journal of materials science. Materials in medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 92 citations in OpenAlex.
- Electrophoretic deposition of hydroxyapatite-capsaicin nanocomposite coatings on Mg-Ag alloy: effects on microstructure, hardness, and proliferation/chondrogenic differentiation of adipose-derived stem cells.Frontiers in bioengineering and biotechnology · 2026Article
- A review of cytotoxicity testing methods and in vitro study of biodegradable Mg-1%Sn-2%HA composite by elution method.Journal of materials science. Materials in medicine · 2025Review
- Review
- A "built-up" composite film with synergistic functionalities on Mg-2Zn-1Mn bioresorbable stents improves corrosion control effects and biocompatibility.Bioactive materials · 2023Article
- Comprehensive review of additively manufactured biodegradable magnesium implants for repairing bone defects from biomechanical and biodegradable perspectives.Frontiers in chemistry · 2022Article
- Fluoride Coatings on Magnesium Alloy Implants.Bioinorganic chemistry and applications · 2022Review
- Article
- Bioabsorbable Osteofixation Materials for Maxillofacial Bone Surgery: A Review on Polymers and Magnesium-Based Materials.Biomedicines · 2020Review
- Optimizing an Osteosarcoma-Fibroblast Coculture Model to Study Antitumoral Activity of Magnesium-Based Biomaterials.International journal of molecular sciences · 2020Article
- Magnesium degradation under physiological conditions - Best practice.Bioactive materials · 2018Review
- Hydroxyapatite (HA)/poly-L-lactic acid (PLLA) dual coating on magnesium alloy under deformation for biomedical applications.Journal of materials science. Materials in medicine · 2016Article
- Similarities and differences in coatings for magnesium-based stents and orthopaedic implants.Journal of orthopaedic translation · 2014Article
- Endothelialization of novel magnesium-rare earth alloys with fluoride and collagen coating.International journal of molecular sciences · 2014Article
- Monetite and brushite coated magnesium: in vivo and in vitro models for degradation analysis.Journal of materials science. Materials in medicine · 2014Article
- Fluoride and calcium-phosphate coated sponges of the magnesium alloy AX30 as bone grafts: a comparative study in rabbits.Journal of materials science. Materials in medicine · 2013Article
- Porous biodegradable metals for hard tissue scaffolds: a review.International journal of biomaterials · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydroxyapatite (HA) was coated onto pure magnesium (Mg) with an MgF(2) interlayer in order to reduce the surface corrosion rate and enhance the biocompatibility. Both MgF(2) and HA were successfully coated in sequence with good adhesion properties using the fluoride conversion coating and aerosol deposition techniques, respectively. In a simulated body fluid (SBF), the double layer coating remarkably enhanced the corrosion resistance of the coated Mg specimen. The in vitro cellular responses of the MC3T3-E1 pre-osteoblasts were examined using a cell proliferation assay and an alkaline phosphatase (ALP) assay, and these results demonstrated that the double coating layer also enhanced cell proliferation and differentiation levels. In the in vivo study, the HA/MgF(2) coated Mg corroded less than the bare Mg and had a higher bone-to-implant contact (BIC) ratio in the cortical bone area of the rabbit femora 4 weeks after implantation. These in vitro and in vivo results suggested that the HA coated Mg with the MgF(2) interlayer could be used as a potential candidate for biodegradable implant materials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.