ArticlePhysics in medicine and biology2011
Viscoelastic properties of soft gels: comparison of magnetic resonance elastography and dynamic shear testing in the shear wave regime.
Article in Physics in medicine and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 97 citations in OpenAlex.
- Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Pharmacological Targeting of Midkine (MDK) Reveals Stiffness-Dependent Control of Hepatocellular Carcinoma Invasiveness.International journal of molecular sciences · 2026Article
- Multiscale measurement of brain tissue and cell biomechanics using a mouse model.Biophysics reports · 2025Article
- 3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms.Journal of the mechanical behavior of biomedical materials · 2025Article
- Birth mode is associated with layer-specific mechanical changes in fetal membranes.Scientific reports · 2025Article
- Mechanically anisotropic phantoms for magnetic resonance elastography.Magnetic resonance in medicine · 2025Article
- Post-mortem changes of anisotropic mechanical properties in the porcine brain assessed by MR elastography.Brain multiphysics · 2024Article
- Viscoelastic polyacrylamide MR elastography phantoms with tunable damping ratio independent of shear stiffness.Journal of the mechanical behavior of biomedical materials · 2024Article
- Mechanical stiffness and anisotropy measured by MRE during brain development in the minipig.NeuroImage · 2023Article
- Design and characterization of 3-D printed hydrogel lattices with anisotropic mechanical properties.Journal of the mechanical behavior of biomedical materials · 2023Article
- OSCILLATE: A low-rank approach for accelerated magnetic resonance elastography.Magnetic resonance in medicine · 2022Article
- Quantitative effects of off-resonance related distortion on brain mechanical property estimation with magnetic resonance elastography.NMR in biomedicine · 2022Article
- MR elastography: Principles, guidelines, and terminology.Magnetic resonance in medicine · 2021Review
- A heterogenous, time harmonic, nearly incompressible transverse isotropic finite element brain simulation platform for MR elastography.Physics in medicine and biology · 2021Article
- Utility of preoperative meningioma consistency measurement with magnetic resonance elastography (MRE): a review.Neurosurgical review · 2019Review
- Dispersion in Tissue-Mimicking Gels Measured with Shear Wave Elastography and Torsional Vibration Rheometry.Ultrasound in medicine & biology · 2019Article
- Analytical solution for diverging elliptic shear wave in bounded and unbounded transverse isotropic viscoelastic material with nonhomogeneous inner boundary.The Journal of the Acoustical Society of America · 2019Article
- Stiffness reconstruction methods for MR elastography.NMR in biomedicine · 2018Review
- Artificial neural networks for stiffness estimation in magnetic resonance elastography.Magnetic resonance in medicine · 2018Article
- Pre-clinical MR elastography: Principles, techniques, and applications.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Magnetic resonance elastography (MRE) is used to quantify the viscoelastic shear modulus, G*, of human and animal tissues. Previously, values of G* determined by MRE have been compared to values from mechanical tests performed at lower frequencies. In this study, a novel dynamic shear test (DST) was used to measure G* of a tissue-mimicking material at higher frequencies for direct comparison to MRE. A closed-form solution, including inertial effects, was used to extract G* values from DST data obtained between 20 and 200 Hz. MRE was performed using cylindrical 'phantoms' of the same material in an overlapping frequency range of 100-400 Hz. Axial vibrations of a central rod caused radially propagating shear waves in the phantom. Displacement fields were fit to a viscoelastic form of Navier's equation using a total least-squares approach to obtain local estimates of G*. DST estimates of the storage G' (Re[G*]) and loss modulus G″ (Im[G*]) for the tissue-mimicking material increased with frequency from 0.86 to 0.97 kPa (20-200 Hz, n = 16), while MRE estimates of G' increased from 1.06 to 1.15 kPa (100-400 Hz, n = 6). The loss factor (Im[G*]/Re[G*]) also increased with frequency for both test methods: 0.06-0.14 (20-200 Hz, DST) and 0.11-0.23 (100-400 Hz, MRE). Close agreement between MRE and DST results at overlapping frequencies indicates that G* can be locally estimated with MRE over a wide frequency range. Low signal-to-noise ratio, long shear wavelengths and boundary effects were found to increase residual fitting error, reinforcing the use of an error metric to assess confidence in local parameter estimates obtained by MRE.
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