ArticlePlant physiology2011
Light-dependent regulation of DEL1 is determined by the antagonistic action of E2Fb and E2Fc.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 60 citations in OpenAlex.
- The genomic basis of the plant island syndrome in Darwin's giant daisies.Nature communications · 2022Article
- Molecular Analysis of the E2F/DP Gene Family ofFrontiers in plant science · 2021Article
- E2FB Interacts with RETINOBLASTOMA RELATED and Regulates Cell Proliferation during Leaf Development.Plant physiology · 2020Article
- E2FA and E2FB transcription factors coordinate cell proliferation with seed maturation.Development (Cambridge, England) · 2019Article
- The developmental dynamics of the Populus stem transcriptome.Plant biotechnology journal · 2019Article
- Polyploidy in tissue homeostasis and regeneration.Development (Cambridge, England) · 2018Review
- Endoreplication: The Good, the Bad, and the Ugly.Trends in cell biology · 2018Review
- Converging Light, Energy and Hormonal Signaling Control Meristem Activity, Leaf Initiation, and Growth.Plant physiology · 2018Article
- The Canonical E2Fs Are Required for Germline Development in Arabidopsis.Frontiers in plant science · 2018Article
- Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.The Plant cell · 2018Article
- Article
- Investigating Triticeae anther gene promoter activity in transgenic Brachypodium distachyon.Planta · 2017Article
- HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.Frontiers in plant science · 2017Article
- Distinctive features and differential regulation of the DRTS genes of Arabidopsis thaliana.PloS one · 2017Article
- Core cell cycle regulatory genes in rice and their expression profiles across the growth zone of the leaf.Journal of plant research · 2015Article
- A Dynamic Gene Regulatory Network Model That Recovers the Cyclic Behavior of Arabidopsis thaliana Cell Cycle.PLoS computational biology · 2015Article
- Promoter-based integration in plant defense regulation.Plant physiology · 2014Article
- The ASH1-RELATED3 SET-domain protein controls cell division competence of the meristem and the quiescent center of the Arabidopsis primary root.Plant physiology · 2014Article
- The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription.PLoS genetics · 2014Article
- At the intersection of plant growth and immunity.Cell host & microbe · 2014Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Endoreduplication represents a variation on the cell cycle in which multiple rounds of DNA replication occur without subsequent chromosome separation and cytokinesis, thereby increasing the cellular DNA content. It is known that the DNA ploidy level of cells is controlled by external stimuli such as light; however, limited knowledge is available on how environmental signals regulate the endoreduplication cycle at the molecular level. Previously, we had demonstrated that the conversion from a mitotic cell cycle into an endoreduplication cycle is controlled by the atypical E2F transcription factor, DP-E2F-LIKE1 (DEL1), that represses the endocycle onset. Here, the Arabidopsis (Arabidopsis thaliana) DEL1 gene was identified as a transcriptional target of the classical E2Fb and E2Fc transcription factors that antagonistically control its transcript levels through competition for a single E2F cis-acting binding site. In accordance with the reported opposite effects of light on the protein levels of E2Fb and E2Fc, DEL1 transcription depended on the light regime. Strikingly, modified DEL1 expression levels uncoupled the link between light and endoreduplication in hypocotyls, implying that DEL1 acts as a regulatory connection between endocycle control and the photomorphogenic response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.