Evidence map›Paper›PMID 21907958›Full record

ArticleAmerican journal of obstetrics and gynecology2011

Rotating nightshift work and the risk of endometriosis in premenopausal women.

Eva S Schernhammer, Allison F Vitonis, Janet Rich-Edwards, Stacey A Missmer

Abstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Occupational risk factors for endometriosis in a cohort of flight attendants.Scandinavian journal of work, environment & health · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eva S SchernhammerChanning Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. eva.schernhammer@channing.harvard.edu
Allison F Vitonis
Janet Rich-Edwards
Stacey A Missmer

Funding

Risk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3M
Statistical Analysis and ProgrammingU19CA055075 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2010 to 2011
$8.4M
Immunology, Inflammation, and EndometriosisR01HD057210 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2009 to 2012
$1.4M
Endogenous Hormones and Risk of EndometriosisR01HD052473 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2006 to 2009
$1.1M
NCI NIH HHS CA050385NCI NIH HHS R01 CA050385NCI NIH HHS U19 CA055075NICHD NIH HHS HD057210NICHD NIH HHS HD52473NICHD NIH HHS R01 HD052473
6 · The paper itself

Abstract

objectiveThe purpose of this prospective study was to study the association between rotating nightshift work and endometriosis risk within the Nurses' Health Study II. STUDY

designWe found 89,400 women without diagnosed endometriosis at baseline; the 2062 laparoscopically confirmed cases that were documented during 16 years of follow-up evaluation formed our study population.

resultsOverall, there was no association between rotating nightshift work and risk of endometriosis. When the cases were categorized by infertility status, risk was elevated among women with concurrent infertility and ≥5 years of rotating nightshift work (rate ratio, 1.71; 95% confidence interval, 1.18-2.49; P(trend) = .005), compared with women with no rotating nightshift work. In contrast, there was no association among women without reported infertility (P(heterogeneity) = .003).

conclusionWomen who work rotating nightshifts for ≥5 years may have a modestly elevated risk of endometriosis if concurrently infertile. However, the relation between shiftwork, endometriosis, and infertility is complex, and the potential for bias because of a healthy or infertile worker effect must be considered.

Indexed as

WorkplaceAdultCircadian RhythmEndometriosisFemaleHumansPremenopauseProspective StudiesRiskRisk FactorsWorkWork Schedule Tolerance

Identifiers

PMID21907958
PMCPMC3205317

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.