Evidence map›Paper›PMID 21907916›Full record

ArticleCancer cell2011

Cancer biomarkers: closer to delivering on their promise.

Lance A Liotta, Emanuel Petricoin

Open access · bronzeAbstract readComment
In one paragraph

Article in Cancer cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Molecular biomarkers in glaucoma.Investigative ophthalmology & visual science · 2013
    Article
  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lance A LiottaCenter for Applied Proteomics and Molecular Medicine, George Mason University, Fairfax, VA, USA. lliotta@gmu.edu
Emanuel Petricoin
George Mason University · US

Funding

Nanotrap technology for one step preservation and amplification of cancer biomarkR33CA173359 · NCI · GEORGE MASON UNIVERSITY · PI LIOTTA, LANCE ALLEN · 2012 to 2014
$1.1M
Implementation of phosphoprotein preservation technology for cancer biospecimensR33CA157403 · NCI · GEORGE MASON UNIVERSITY · PI LIOTTA, LANCE ALLEN · 2011 to 2013
$922k
Nanotechnology for One Step Concentration and Preservation of Labile Biomarkers iR21CA137706 · NCI · GEORGE MASON UNIVERSITY · PI LIOTTA, LANCE ALLEN · 2009 to 2010
$530k
Phosphorylated signal pathway proteins: A new class of vitreous biomarkers for opR21EY018942 · NEI · GEORGE MASON UNIVERSITY · PI LIOTTA, LANCE ALLEN · 2008 to 2009
$376k
A non-invasive nanotechnology-based skin patch for multiplexed diagnosticsR21AR061075 · NIAMS · GEORGE MASON UNIVERSITY · PI LIOTTA, LANCE ALLEN · 2011 to 2012
$360k
Surrogate and Sentinal Technologies to Monitor Stability of Cancer PhosphoproteinR21CA125698 · NCI · GEORGE MASON UNIVERSITY · PI LIOTTA, LANCE ALLEN · 2008 to 2009
$330k
NCI NIH HHS R21 CA125698NCI NIH HHS R21 CA137706NCI NIH HHS R33 CA157403NCI NIH HHS R33 CA173359NEI NIH HHS R21 EY018942NIAMS NIH HHS R21 AR061075
6 · The paper itself

Abstract

Taguchi et al. describe, in this issue of Cancer Cell, a quantitative comparative biomarker discovery approach that integrates animal lung cancer models with validation in well-controlled human clinical study sets. This approach overcomes many of the major barriers that have held back the field of cancer biomarkers in the past.

Identifiers

PMID21907916
PMCPMC3783266
OpenAlexW1993105671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.