Evidence map›Paper›PMID 21907520›Full record

ArticleMagnetic resonance imaging2011

Alterations in diffusion properties of white matter in Williams syndrome.

Lori R Arlinghaus, Tricia A Thornton-Wells, Elisabeth M Dykens, Adam W Anderson

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Reprint of: Mapping connectivity in the developing brain.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2014
    Article
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  11. Mapping connectivity in the developing brain.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2013
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lori R ArlinghausInstitute of Imaging Science, Vanderbilt University, Nashville, TN, USA. lori.arlinghaus@vanderbilt.edu
Tricia A Thornton-Wells
Elisabeth M Dykens
Adam W Anderson
Vanderbilt University · USVanderbilt Health · US

Funding

MOLECULAR BEACONS FOR RETROVIRAL DIAGNOSTICSR01EB000277 · NIBIB · PUBLIC HEALTH RESEARCH INSTITUTE · PI KRAMER, FRED R · 2002 to 2004
$1.8M
Improved imaging of brain white matterR01EB002777 · NIBIB · VANDERBILT UNIVERSITY · PI ANDERSON, ADAM W · 2003 to 2007
$1.2M
NIBIB NIH HHS R01 EB000277NIBIB NIH HHS R01 EB00277NIBIB NIH HHS R01 EB002777
6 · The paper itself

Abstract

Diffusion tensor imaging (DTI) was used to investigate the involvement of brain white matter in Williams syndrome (WS), a genetic neurodevelopmental disorder. Whole-brain DTIs were obtained from 16 young adults with WS and 16 normal controls. A voxel-based analysis was performed to compare fractional anisotropy (FA) values between the two groups. A tract-based analysis was also performed to compare FA values between the two groups along two major white matter tracts that pass through the external capsule: the uncinate and inferior fronto-occipital fasciculi. Several regions of both increased and decreased FA were found within major white matter tracts that connect functional regions that have previously been implicated in the cognitive and neurological symptoms of the syndrome. The tract-based analysis provided additional insight into the involvement of specific white matter tracts implicated in the voxel-based analysis within the external capsule. The results from this study support previously reported changes in white matter diffusion properties in WS and demonstrate the potential usefulness for tract-based analysis in future studies of the disorder.

Indexed as

AdolescentAdultAnisotropyBrainBrain MappingCerebrovascular CirculationDiffusionDiffusion Tensor ImagingFemaleFrontal LobeHumansImage Processing, Computer-AssistedMaleNerve Fibers, MyelinatedOccipital LobeWilliams Syndrome

Identifiers

PMID21907520
PMCPMC3199335
OpenAlexW2125096937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.