Evidence map›Paper›PMID 21907427›Full record

ArticleInternational journal of cardiology2012

A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward).

John J Ryan, Matthew Kalscheur, Lisa Dellefave, Elizabeth McNally, Stephen L Archer

Abstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Functional Profiling ofCirculation. Genomic and precision medicine · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John J Ryan
Matthew Kalscheur
Lisa Dellefave
Elizabeth McNally
Stephen L Archer

Funding

SARCOGLYCAN IN MYOPATHY AND MUSCLE MEMBRANE STABILITYR01HL061322 · NHLBI · UNIVERSITY OF CHICAGO · PI MCNALLY, ELIZABETH M · 1999 to 2022
$7.5M
Myoferlin in Muscle Membrane Fusion and RepairR01NS047726 · NINDS · UNIVERSITY OF CHICAGO · PI ALEXIS R. DEMONBREUN, Elizabeth M McNally · 2003 to 2026
$7.2M
O2 sensing in the human and rabbit ductus arteriosus.R01HL071115 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2004 to 2015
$3.1M
Sulfonylurea KATP channels in vascular spasmR01HL078926 · NHLBI · UNIVERSITY OF CHICAGO · PI MCNALLY, ELIZABETH M · 2005 to 2009
$1.8M
The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial HypertensionR01HL113003 · NHLBI · QUEEN'S UNIVERSITY AT KINGSTON · PI ARCHER, STEPHEN L · 2013 to 2016
$1.1M
Impaired mitochondrial fusion in pulmonary arterial hypertensionRC1HL099462 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2009 to 2010
$1.0M
NHLBI NIH HHS 1RC1HL099462-01NHLBI NIH HHS HL061322NHLBI NIH HHS HL078926NHLBI NIH HHS HL093443NHLBI NIH HHS R01 HL061322NHLBI NIH HHS R01 HL071115NHLBI NIH HHS R01-HL071115NHLBI NIH HHS R01 HL078926NHLBI NIH HHS R01 HL113003NHLBI NIH HHS RC1 HL099462NINDS NIH HHS NS047726NINDS NIH HHS R01 NS047726
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultExerciseFemaleGenetic VariationHumansLong QT SyndromeMutation, MissensePotassium Channels, Voltage-GatedRomano-Ward SyndromeKCNE1 protein, humanPotassium Channels, Voltage-Gated

Identifiers

PMID21907427
PMCPMC3253314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.