ArticleBMC genomics2011
Deep sequencing-based transcriptome analysis of Plutella xylostella larvae parasitized by Diadegma semiclausum.
Article in BMC genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 89 citations in OpenAlex.
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- Identification of Key Genes Involved in Resistance to Early Stage of BmNPV Infection in Silkworms.Viruses · 2022Article
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- Diverse Host Immune Responses of Different Geographical Populations of the Coconut Rhinoceros Beetle to Oryctes Rhinoceros Nudivirus (OrNV) Infection.Microbiology spectrum · 2021Article
- Antibiotics accelerate growth at the expense of immunity.Proceedings. Biological sciences · 2021Article
- The glutathione S-transferase (PxGST2L) may contribute to the detoxification metabolism of chlorantraniliprole in Plutella xylostella(L.).Ecotoxicology (London, England) · 2021Article
- Transcriptome analysis of blood for the discovery of sex-related genes in ricefield eel Monopterus albus.Fish physiology and biochemistry · 2020Article
- Molecular Evidence thatInternational journal of molecular sciences · 2020Article
- Variation in Performance and Resistance to Parasitism ofInsects · 2019Article
- Regulation of the Larval Transcriptome ofFrontiers in physiology · 2019Article
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- Transcriptome-wide analysis of immune-responsive microRNAs against poly (I:C) challenge inOncotarget · 2017Article
- An endoparasitoid wasp influences host DNA methylation.Scientific reports · 2017Article
- The Entomopathogenic FungiFrontiers in microbiology · 2017Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParasitoid insects manipulate their hosts' physiology by injecting various factors into their host upon parasitization. Transcriptomic approaches provide a powerful approach to study insect host-parasitoid interactions at the molecular level. In order to investigate the effects of parasitization by an ichneumonid wasp (Diadegma semiclausum) on the host (Plutella xylostella), the larval transcriptome profile was analyzed using a short-read deep sequencing method (Illumina). Symbiotic polydnaviruses (PDVs) associated with ichneumonid parasitoids, known as ichnoviruses, play significant roles in host immune suppression and developmental regulation. In the current study, D. semiclausum ichnovirus (DsIV) genes expressed in P. xylostella were identified and their sequences compared with other reported PDVs. Five of these genes encode proteins of unknown identity, that have not previously been reported.
resultsDe novo assembly of cDNA sequence data generated 172,660 contigs between 100 and 10000 bp in length; with 35% of > 200 bp in length. Parasitization had significant impacts on expression levels of 928 identified insect host transcripts. Gene ontology data illustrated that the majority of the differentially expressed genes are involved in binding, catalytic activity, and metabolic and cellular processes. In addition, the results show that transcription levels of antimicrobial peptides, such as gloverin, cecropin E and lysozyme, were up-regulated after parasitism. Expression of ichnovirus genes were detected in parasitized larvae with 19 unique sequences identified from five PDV gene families including vankyrin, viral innexin, repeat elements, a cysteine-rich motif, and polar residue rich protein. Vankyrin 1 and repeat element 1 genes showed the highest transcription levels among the DsIV genes.
conclusionThis study provides detailed information on differential expression of P. xylostella larval genes following parasitization, DsIV genes expressed in the host and also improves our current understanding of this host-parasitoid interaction.
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