ArticleAutism research : official journal of the International Society for Autism Research2012
Evidence for broader autism phenotype characteristics in parents from multiple-incidence autism families.
Article in Autism research : official journal of the International Society for Autism Research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 100 citations in OpenAlex.
- Broader autism phenotype, the default mode network, and brain entropy: A network-level hypothesis.Research in neurodiversity · 2026Article
- Narrative and visual attention in autism spectrum disorder: a cross-cultural perspective.Frontiers in psychiatry · 2026Article
- Narrative Ability in Autism and First-Degree Relatives.Journal of autism and developmental disorders · 2025Article
- Exploring autistic traits in parents of autistic children: a pilot study on the broader autism phenotype.Frontiers in psychiatry · 2025Article
- Context effects: discourse structure influences narrative ability in autism and first-degree relatives.Frontiers in psychiatry · 2025Article
- Associations between paternal autism traits and parenting from the Japan environment and children's study.Scientific reports · 2024Article
- Childhood Academic Performance: A Potential Marker of Genetic Liability to Autism.Journal of autism and developmental disorders · 2023Article
- "Peas in a pod": Oral History Reflections on Autistic Identity in Family and Community by Late-Diagnosed Adults.Journal of autism and developmental disorders · 2023Article
- Reading the room: Autistic traits, gaze behaviour, and the ability to infer social relationships.PloS one · 2023Article
- Three decades of ASD genetics: building a foundation for neurobiological understanding and treatment.Human molecular genetics · 2021Article
- Genetic counseling as preventive intervention: toward individual specification of transgenerational autism risk.Journal of neurodevelopmental disorders · 2021Article
- Characterizing Emotion Recognition and Theory of Mind Performance Profiles in Unaffected Siblings of Autistic Children.Frontiers in psychology · 2021Article
- Relational Uncertainty and Taking Conflict Personally: Comparing Parents of Children with and Without Autism Spectrum Disorder.Journal of autism and developmental disorders · 2020Article
- Understanding Social Communication Differences in Autism Spectrum Disorder and First-Degree Relatives: A Study of Looking and Speaking.Journal of autism and developmental disorders · 2020Article
- Theory of Mind Performance in Broad Autism Phenotype Groups: Between-Group Differences and Predictor Variables.Journal of autism and developmental disorders · 2019Article
- Social complexity and the early social environment affect visual social attention to faces.Autism research : official journal of the International Society for Autism Research · 2019Article
- Replication of a rare risk haplotype on 1p36.33 for autism spectrum disorder.Human genetics · 2018Article
- Broader autism phenotype in parents of children with autism: a systematic review of percentage estimates.Journal of child and family studies · 2018Article
- Predicting Internalizing and Externalizing Symptoms in Children with ASD: Evaluation of a Contextual Model of Parental Factors.Journal of autism and developmental disorders · 2018Article
- Developmental Markers of Genetic Liability to Autism in Parents: A Longitudinal, Multigenerational Study.Journal of autism and developmental disorders · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The broader autism phenotype (BAP) was assessed in parents who have two or more children with autism spectrum disorder (ASD) (multiplex (MPX) autism), parents who have no more than one child with ASD (simplex autism), parents who have a child with developmental delay without ASD, and parents who have typically developing children. Clinicians, naive to parent group membership status, rated BAP characteristics from videotaped administration of the Broader Autism Phenotype Symptom Scale (BPASS). Differences among groups in BPASS scores in the four assessed domains (social motivation, conversational skills, expressiveness, and restricted interests) were examined using multivariate ANOVA and post hoc comparisons. Further, ratings of videotapes by observers naïve to family status were compared with live, non-naive ratings by observers who were aware of family status (non-naïve). Findings demonstrate that the BPASS is an instrument resistant to rater bias. Parents from MPX autism families showed significantly more autism phenotype characteristics than the parents in the other groups. Moreover, the parents from simplex autism families did not differ from the parents of children with developmental delay or typical development. Finally, no differences between live, non-naive ratings and videotaped, naive ratings were observed. These findings suggest that characteristics of the BAP, specifically in the social and communication domains, are present in MPX autism parents to a greater degree than simplex autism and control parents. Further, the results provide support for the notion that genetic transmission mechanisms may differ between families with more than one child with autism and families with only one child with autism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.