ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2011
Myelin regeneration in multiple sclerosis: targeting endogenous stem cells.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 55 citations in OpenAlex.
- Oligodendroglia as Active Immunomodulators in Demyelinating Diseases.Neuroscience bulletin · 2026Review
- Molecular cues from distinct neuron classes drive differential myelination in the neocortex.Developmental cell · 2026Article
- Routes of precursors' migration in remyelination.Brain : a journal of neurology · 2026Review
- Oligodendrocyte precursor cell AMPA receptors differ with age and brain region while kainate receptors remain stable.iScience · 2025Article
- Repair mechanisms of the central nervous system: From axon sprouting to remyelination.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Remyelination as a therapeutic target in the treatment of multiple sclerosis.AIMS neuroscience · 2025Review
- Oligodeoxynucleotide IMT504: Effects on Central Nervous System Repair Following Demyelination.Molecular neurobiology · 2024Article
- Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells.Nature communications · 2024Article
- Translation of cell therapies to treat autoimmune disorders.Advanced drug delivery reviews · 2024Review
- Signaling mechanisms involved in the regulation of remyelination in multiple sclerosis: a mini review.Journal of molecular medicine (Berlin, Germany) · 2023Review
- Newly Identified Deficiencies in the Multiple Sclerosis Central Nervous System and Their Impact on the Remyelination Failure.Biomedicines · 2022Review
- White Matter Stroke Induces a Unique Oligo-Astrocyte Niche That Inhibits Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Co-administration of aspirin and adipose-derived stem cell conditioned medium improves the functional recovery of the optic pathway in a lysolecithin-induced demyelination model.Neuropsychiatric disease and treatment · 2019Article
- Muscarinic Receptor MThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Correlated Heterospectral Lipidomics for Biomolecular Profiling of Remyelination in Multiple Sclerosis.ACS central science · 2018Article
- Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation.Nature chemical biology · 2018Article
- Stem Cell-Mediated Regeneration of the Adult Brain.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016Review
- The scales and tales of myelination: using zebrafish and mouse to study myelinating glia.Brain research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
Regeneration of myelin sheaths (remyelination) after central nervous system demyelination is important to restore saltatory conduction and to prevent axonal loss. In multiple sclerosis, the insufficiency of remyelination leads to the irreversible degeneration of axons and correlated clinical decline. Therefore, a regenerative strategy to encourage remyelination may protect axons and improve symptoms in multiple sclerosis. We highlight recent studies on factors that influence endogenous remyelination and potential promising pharmacological targets that may be considered for enhancing central nervous system remyelination.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.