Evidence map›Paper›PMID 21904677›Full record

ArticleInternational journal of nephrology2011

Molecular and genetic basis of inherited nephrotic syndrome.

Maddalena Gigante, Matteo Piemontese, Loreto Gesualdo, Achille Iolascon, Filippo Aucella

Open access · goldAbstract read
In one paragraph

Article in International journal of nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Congenital nephrotic syndrome.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Review
  6. Article
  7. Mechanisms of Proteinuria in HIV.Frontiers in medicine · 2021
    Review
  8. Article
  9. The Role of p.Ser1105Ser (inMedicina (Kaunas, Lithuania) · 2019
    Article
  10. Review
  11. Article
  12. Review
  13. Membrane trafficking in podocyte health and disease.Pediatric nephrology (Berlin, Germany) · 2013
    Review
  14. Nephrotic syndrome.Indian journal of pediatrics · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Maddalena GiganteDivision of Nephrology, Department of Biomedical Science, University of Foggia, 71121 Foggia, Italy.
Matteo Piemontese
Loreto Gesualdo
Achille Iolascon
Filippo Aucella
Casa Sollievo della Sofferenza · ITUniversity of Foggia · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephrotic syndrome is an heterogeneous disease characterized by increased permeability of the glomerular filtration barrier for macromolecules. Podocytes, the visceral epithelial cells of glomerulus, play critical role in ultrafiltration of plasma and are involved in a wide number of inherited and acquired glomerular diseases. The identification of mutations in nephrin and other podocyte genes as causes of genetic forms of nephrotic syndrome has revealed new important aspects of the pathogenesis of proteinuric kidney diseases and expanded our knowledge of the glomerular biology. Moreover, a novel concept of a highly dynamic slit diaphragm proteins is emerging. The most significant discoveries in our understanding of the structure and function of the glomerular filtration barrier are reviewed in this paper.

Identifiers

PMID21904677
PMCPMC3167185
OpenAlexW2122072030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.