ArticleActa crystallographica. Section F, Structural biology and crystallization communications2011
Gene Composer in a structural genomics environment.
Article in Acta crystallographica. Section F, Structural biology and crystallization communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.Acta crystallographica. Section F, Structural biology communications · 2015Article
- A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.Antimicrobial agents and chemotherapy · 2014Article
- Structure and function of a cyanophage-encoded peptide deformylase.The ISME journal · 2013Article
- Artificial neural networks trained to detect viral and phage structural proteins.PLoS computational biology · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The structural genomics effort at the Seattle Structural Genomics Center for Infectious Disease (SSGCID) requires the manipulation of large numbers of amino-acid sequences and the underlying DNA sequences which are to be cloned into expression vectors. To improve efficiency in high-throughput protein structure determination, a database software package, Gene Composer, has been developed which facilitates the information-rich design of protein constructs and their underlying gene sequences. With its modular workflow design and numerous graphical user interfaces, Gene Composer enables researchers to perform all common bioinformatics steps used in modern structure-guided protein engineering and synthetic gene engineering. An example of the structure determination of H1N1 RNA-dependent RNA polymerase PB2 subunit is given.
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Registered trials
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