ArticleAJNR. American journal of neuroradiology2011
Apparent diffusion coefficient with higher b-value correlates better with viable cell count quantified from the cavity of brain abscess.
Article in AJNR. American journal of neuroradiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Imaging-based predictors of progression in brain abscess: the role of loculation and ADC gradient.Acta neurochirurgica · 2026Article
- Medical and Neurological Management of Brain Tumor Complications.Current neurology and neuroscience reports · 2021Review
- Role of Diffusion-Weighted Imaging in the Evaluation of Perianal Fistulae.The Indian journal of radiology & imaging · 2021Article
- Potential of diffusion-weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra-high b-value diffusion-weighted imaging.Oncology letters · 2019Article
- Article
- Noninvasive Quantification of Cell Density in Three-Dimensional Gels by MRI.IEEE transactions on bio-medical engineering · 2019Article
- Article
- Efficient experimental designs for isotropic generalized diffusion tensor MRI (IGDTI).Magnetic resonance in medicine · 2018Article
- MR imaging biomarkers for evaluating therapeutic effects shortly after near infrared photoimmunotherapy.Oncotarget · 2016Article
- The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2014Review
- Article
- Diffusion-weighted MRI of abscess formations in children and young adults.World journal of pediatrics : WJP · 2012Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDWI by using higher b-values provides tissue diffusivity with less T2 shinethrough effect. VCD in the abscess cavity correlates with ADC values. The purpose of this study was to investigate which b-value-derived ADC correlates better with VCD. MATERIALS AND
methodsThirty patients with brain abscess underwent conventional MR imaging and DWI with b = 1000, 2000, and 3000 s/mm(2) on a 3T MR imaging scanner. ADC values were quantified by placing regions of interest inside the abscess cavity in all sections where the lesion was apparent on coregistered ADC maps derived from different b-values. VCD was measured on pus aspirated.
resultsAn increase in b-value was associated with a decrease in ADC values in normal parenchyma as well as in the abscess cavity. The most significant negative correlation of VCD was observed with b = 3000 s/mm(2) (r = -0.98, P = .01).
conclusionsVCD in the abscess cavity can be best assessed at b = 3000 s/mm(2) secondary to the reduction in the T2 shinethrough effect. DWI with b = 3000 s/mm(2) is of promising value in the assessment of the therapeutic response of brain abscess.
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