Evidence map›Paper›PMID 21903397›Full record

ReviewTrends in biochemical sciences2011

A brief survey of mRNA surveillance.

Ambro van Hoof, Eric J Wagner

Abstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Down-Regulation of Rice Glutelin byInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. The roles of RNA processing in translating genotype to phenotype.Nature reviews. Molecular cell biology · 2017
    Review
  11. Ribosome-based quality control of mRNA and nascent peptides.Wiley interdisciplinary reviews. RNA · 2017
    Review
  12. Article
  13. Quantitative proteomic analyses of mammary organoids reveals distinct signatures after exposure to environmental chemicals.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  14. Ribosome-associated protein quality control.Nature structural & molecular biology · 2016
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Protein homeostasis at the plasma membrane.Physiology (Bethesda, Md.) · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ambro van HoofDepartment of Microbiology and Molecular Genetics, University of Texas Health Science Center-Houston, 6431 Fannin Street, Houston, TX 77030, USA. ambro.van.hoof@uth.tmc.edu
Eric J Wagner

Funding

METABOLISM OF YEAST mRNAS THAT LACK A STOP CODONR01GM069900 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI VAN HOOF, AMBRO · 2005 to 2009
$1.4M
Characterizing Novel Components Involved in 3' End Processing of Histone pre-mRNAR00GM080447 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WAGNER, ERIC J · 2008 to 2010
$745k
Assay for Compounds that Elicit Misprocessing of Small Nuclear RNAR21NS067660 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WAGNER, ERIC J · 2009 to 2009
$150k
NIGMS NIH HHS 5R00GM080447NIGMS NIH HHS R00 GM080447NIGMS NIH HHS R01 GM069900NIGMS NIH HHS R01GM069900NINDS NIH HHS 1R21NS0676601NINDS NIH HHS R21 NS067660
6 · The paper itself

Abstract

Defective mRNAs are degraded more rapidly than normal mRNAs in a process called mRNA surveillance. Eukaryotic cells use a variety of mechanisms to detect aberrations in mRNAs and a variety of enzymes to preferentially degrade them. Recent advances in the field of RNA surveillance have provided new information regarding how cells determine which mRNA species should be subject to destruction and novel mechanisms by which a cell tags an mRNA once such a decision has been reached. In this review, we highlight recent progress in our understanding of these processes.

Indexed as

AnimalsHumansRNA, MessengerRNA StabilityRNA, Messenger

Identifiers

PMID21903397
PMCPMC3205232

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.