ArticleNeuron2011
Rapid plasticity of visual responses in the adult lateral geniculate nucleus.
Article in Neuron, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Adaptation of visual responses in degeneratingFrontiers in neuroscience · 2026Article
- Limited transmission of mixed convergent signals at the mouse retinogeniculate synapse.Neuron · 2025Article
- Effects of taurine, brimonidine and betaxolol on oscillation modulation and stimulation efficiency in degenerated rd10 mouse retinas.Scientific reports · 2025Article
- Effects of Hydrostatic Pressure on Electrical Retinal Activity in a Multielectrode Array-BasedFrontiers in neuroscience · 2022Article
- Development of Functional Properties in the Early Visual System: New Appreciations of the Roles of Lateral Geniculate Nucleus.Current topics in behavioral neurosciences · 2022Review
- Synchrony of Spontaneous Burst Firing between Retinal Ganglion Cells Across Species.Experimental neurobiology · 2020Article
- Article
- Refinement of Spatial Receptive Fields in the Developing Mouse Lateral Geniculate Nucleus Is Coordinated with Excitatory and Inhibitory Remodeling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Lateral geniculate neurons projecting to primary visual cortex show ocular dominance plasticity in adult mice.Nature neuroscience · 2017Article
- Article
- An evolving view of retinogeniculate transmission.Visual neuroscience · 2017Review
- Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Cortical brightness adaptation when darkness and brightness produce different dynamical states in the visual cortex.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Orientation-selective responses in the mouse lateral geniculate nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Spatiotemporal receptive field structures in retinogeniculate connections of cat.Frontiers in systems neuroscience · 2013Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Compared to the developing visual system, where neuronal plasticity has been well characterized at multiple levels, little is known about plasticity in the adult, particularly within subcortical structures. We made intraocular injections of 2-amino-4-phosphonobutyric acid (APB) in adult cats to block visual responses in On-center retinal ganglion cells and examined the consequences on visual responses in the lateral geniculate nucleus (LGN) of the thalamus. In contrast to current views of retinogeniculate organization, which hold that On-center LGN neurons should become silent with APB, we find that ∼50% of On-center neurons rapidly develop Off-center responses. The time course of these emergent responses and the actions of APB in the retina indicate the plasticity occurs within the LGN. These results suggest there is greater divergence of retinogeniculate connections than previously recognized and that functionally silent, nonspecific retinal inputs can serve as a substrate for rapid plasticity in the adult.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.