ArticleJSLS : Journal of the Society of Laparoendoscopic Surgeons
Routine testing of liver function before and after elective laparoscopic cholecystectomy: is it necessary?
Article in JSLS : Journal of the Society of Laparoendoscopic Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy.World journal of emergency surgery : WJES · 2021Guideline
- Transient liver enzyme elevations following laparoscopic cholecystectomy: a comprehensive review.Updates in surgery · 2025Review
- Are We Overtesting? Rethinking Routine Blood Work After Low-Risk Laparoscopic Cholecystectomy: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2025Article
- Value and relevance of routine postoperative blood sample analysis after general surgery-a single centre analysis of 1198 patients.Langenbeck's archives of surgery · 2025Article
- Transient Elevation of Liver Function Tests and Bilirubin Levels After Laparoscopic Cholecystectomy.Medicina (Kaunas, Lithuania) · 2024Article
- Article
- Biliary Anatomy Visualization and Surgeon Satisfaction Using Standard Cholangiography versus Indocyanine Green Fluorescent Cholangiography during Elective Laparoscopic Cholecystectomy: A Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Comparison of postoperative outcomes between different dissection techniques during laparoscopic cholecystectomy in rabbits: randomized study.Acta cirurgica brasileira · 2024Article
- Comparative evaluation of three laparoscopic cholecystectomy techniques in rabbit's model.Acta cirurgica brasileira · 2023Article
- [Which patient needs controls of laboratory values after elective laparoscopic cholecystectomy?-Can a score help?]Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Article
- Comparison of postoperative liver function between different dissection techniques during laparoscopic cholecystectomy.Future science OA · 2020Article
- Evaluation and comparison of postoperative levels of serum bilirubin, serum transaminases and alkaline phosphatase in laparoscopic cholecystectomy versus open cholecystectomy.Journal of gastrointestinal oncology · 2015Article
- Cardiac and Liver Marker Alterations After Laparoscopic Gynaecologic Operations.Turkish journal of anaesthesiology and reanimation · 2015Article
- Assessment of gallstone predictor: comparative analysis of ultrasonographic and biochemical parameters.International archives of medicine · 2013Article
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1 author.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesLiver function tests (LFTs) include alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), and bilirubin. The role of routine testing before and after laparoscopic cholecystectomy was evaluated in this study. PATIENTS AND
methodsA total of 355 patients were retrospectively analyzed by examining the LFTs the day before, the day after, and 3 weeks after the surgery. The Wilcoxon signed-rank test and Student t test were performed to determine statistical significance.
resultsAlterations in the serum AST, ALT, and GGT were seen on the first postoperative day. Minor changes were seen in bilirubin and ALP. An overall disturbance in the LFTs was seen in more than two-thirds of the cases. Repeat LFTs performed after 3 weeks on follow-up were found to be within normal limits.
conclusionMild-to-moderate elevation in preoperative LFTs may not be associated with any deleterious effect, and, in the absence of clinical indications, routine preoperative or postoperative liver function testing is unnecessary.
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