ReviewCurrent pharmaceutical design2011
Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.
Review in Current pharmaceutical design, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Review
- Adaptive responses to air pollution in human dermal fibroblasts and their potential roles in aging.FASEB bioAdvances · 2021Article
- The mitochondrial hypothesis: Dysfunction, bioenergetic defects, and the metabolic link to Alzheimer's disease.International review of neurobiology · 2020Review
- Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities.British journal of pharmacology · 2019Review
- Mitochondria, Cybrids, Aging, and Alzheimer's Disease.Progress in molecular biology and translational science · 2017Review
- Dorsal Root Ganglia Mitochondrial Biochemical Changes in Non-diabetic and Streptozotocin-Induced Diabetic Mice Fed with a Standard or High-Fat Diet.Journal of neurology and neuroscience · 2017Article
- Bioenergetics and metabolism: a bench to bedside perspective.Journal of neurochemistry · 2016Review
- Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure.Journal of neurochemistry · 2016Article
- Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer's Disease.Current topics in medicinal chemistry · 2016Review
- Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure.Journal of bioenergetics and biomembranes · 2015Article
- Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2015Review
- Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.Human molecular genetics · 2014Article
- The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.Biochimica et biophysica acta · 2014Review
- Common defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploring.Biochemical pharmacology · 2014Review
- Bioenergetic medicine.British journal of pharmacology · 2014Review
- Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines.Human molecular genetics · 2013Article
- Lactate administration reproduces specific brain and liver exercise-related changes.Journal of neurochemistry · 2013Article
- Beyond amyloid: getting real about nonamyloid targets in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2013Article
- Glycolysis-respiration relationships in a neuroblastoma cell line.Biochimica et biophysica acta · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Several sporadic neurodegenerative diseases display phenomena that directly or indirectly relate to mitochondrial function. Data suggesting altered mitochondrial function in these diseases could arise from mitochondrial DNA (mtDNA) are reviewed. Approaches for manipulating mitochondrial function and minimizing the downstream consequences of mitochondrial dysfunction are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.