ArticleInflammation2012
The IL-10 promoter polymorphism at position -592 is correlated with susceptibility to occult HBV infection.
Article in Inflammation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- HBV biomarkers outperform host genetic variants in distinguishing occult HBV infection from chronic carriers.iScience · 2026Article
- Host Genetic Variations and Their Implications on HBV and HCV Infection in the Iranian Population: A Comprehensive Systematic Review.Iranian journal of public health · 2024Review
- High lymphocyte‑to‑monocyte ratio is associated with low α‑fetoprotein expression in patients with hepatitis B virus‑associated hepatocellular carcinoma.Molecular medicine reports · 2020Article
- Host Genetic Determinants of Hepatitis B Virus Infection.Frontiers in genetics · 2019Review
- Update on occult hepatitis B virus infection.World journal of gastroenterology · 2016Review
- Functional analysis of 'a' determinant mutations associated with occult HBV in HIV-positive South Africans.The Journal of general virology · 2016Article
- Genetic variation of occult hepatitis B virus infection.World journal of gastroenterology · 2016Review
- IL-6 Plays a Crucial Role in HBV Infection.Journal of clinical and translational hepatology · 2015Review
- Levels of Transforming Growth Factor-Beta After Immunization of Mice With in vivo prepared Toxoplasma gondii Excretory/Secretory Proteins.Jundishapur journal of microbiology · 2015Article
- Mutations associated with occult hepatitis B in HIV-positive South Africans.Journal of medical virology · 2015Article
- Effects of interleukin 10 polymorphisms on the development of hepatitis B virus infection: a systemic review and meta-analysis.International journal of clinical and experimental medicine · 2015Article
- The effect of depression and anxiety on expression levels of toll like receptor signaling molecules in chronic HBV infected patients.Medical journal of the Islamic Republic of Iran · 2015Article
- TLR3 plays significant roles against hepatitis B virus.Molecular biology reports · 2014Review
- Article
- No correlation between interleukin-10 gene promoter polymorphisms and hepatitis B virus infection outcome.Hepatitis monthly · 2013Article
- High Serum Levels of TGF-β in Iranians With Chronic HBV Infection.Hepatitis monthly · 2012Article
- The influence of human leukocyte antigen and IL-10 gene polymorphisms on hepatitis B virus outcome.Hepatitis monthly · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Occult hepatitis B infection (OBI) is characterized as a form of hepatitis in which detectable amounts of HBV-DNA can be monitored in the peripheral blood of patients whereas the hepatitis B surface antigen is undetectable. The main aim of this study was to investigate whether there is a relationship between OBI and single nucleotide polymorphisms in the -592 region of the IL-10 gene. In this study, the polymorphism at position -592 of the IL-10 promoter of 57 OBI cases was compared and correlated to that of 100 healthy controls by PCR-RFLP techniques. Our results showed that patient and control groups had significant differences regarding genotypes and alleles of the -592 polymorphism in the IL-10 gene. Based on our results, it can be concluded that the -592 polymorphism within the promoter of the IL-10 gene is associated with OBI.
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Registered trials
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