SynthesisSocial psychiatry and psychiatric epidemiology2012
The age at onset of psychosis and tobacco use: a systematic meta-analysis.
Synthesis in Social psychiatry and psychiatric epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies.Molecular psychiatry · 2022Pooled it
- Cholesterol and triglyceride levels in first-episode psychosis: systematic review and meta-analysis.The British journal of psychiatry : the journal of mental science · 2017Pooled it
- Does tobacco use cause psychosis? Systematic review and meta-analysis.The lancet. Psychiatry · 2015Pooled it
- Why does age of onset predict clinical severity in schizophrenia? A multiplex extended pedigree study.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2020Article
- Adolescent Substance Use and the Brain: Behavioral, Cognitive and Neuroimaging Correlates.Frontiers in human neuroscience · 2020Article
- The relationship between nicotine and psychosis.Therapeutic advances in psychopharmacology · 2019Review
- Characteristics and Predictors of Intention to use Cessation Treatment among Smokers with Schizophrenia: Young Adults Compared to Older Adults.Journal of substance abuse and alcoholism · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a well-established but poorly understood association between tobacco use and psychotic illness. The aim of this study was to determine whether tobacco use is associated with an earlier age at onset of psychotic illness.
methodsPeer-reviewed publications in English reporting the age at onset of psychosis in tobacco-using and non-tobacco-using groups were located using searches of CINAHL, EMBASE, MEDLINE, PsycINFO and ISI Web of Science, and were supplemented by papers located by manual searches and unpublished data obtained by correspondence with primary researchers. A total of 29 samples reported age at onset data in a consecutive series of patients with a diagnosis of schizophrenia related psychosis or first episode psychosis. Information on study design, study population and effect size was extracted independently by three authors. A random effects meta-analysis was performed.
resultsThere was no significant difference between smokers and non-smokers in age at the onset of psychosis (standardized mean difference = -0.03).
conclusionUnlike cannabis use, tobacco use is not associated with an earlier onset of psychosis.
Indexed as
Identifiers
21901400What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.