ArticleDigestive diseases and sciences2012
Small bowel capsule endoscopy impacts diagnosis and management of pediatric inflammatory bowel disease: a prospective study.
Article in Digestive diseases and sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 60 citations in OpenAlex.
- The use of a patency capsule in pediatric Crohn's disease: a prospective evaluation.Digestive diseases and sciences · 2011Trial
- Video capsule endoscopy in very early onset inflammatory bowel disease: a multicenter retrospective study from the Chinese Pediatric VCE Study Group.Translational gastroenterology and hepatology · 2026Article
- Expert consensus on diagnostic guidelines for pediatric inflammatory bowel disease in Japan.Journal of gastroenterology · 2025Review
- Multicenter prospective registration study of efficacy and safety of capsule endoscopy in Crohn's disease in Japan (SPREAD-J study).Journal of gastroenterology · 2023Article
- Evaluation of Crohn's Disease Small-Bowel Mucosal Healing Using Capsule Endoscopy and Usefulness of Leucine-Rich α2-Glycoprotein.Diagnostics (Basel, Switzerland) · 2023Article
- Diagnostic Yields and Clinical Impacts of Capsule Endoscopy.Diagnostics (Basel, Switzerland) · 2021Review
- CEing More-Assessing Small Bowel Crohn's with Capsule Endoscopy (CE).Digestive diseases and sciences · 2021Article
- Capsule Endoscopy in Children.Frontiers in pediatrics · 2021Review
- Comparison of the use of wireless capsule endoscopy with magnetic resonance enterography in children with inflammatory bowel disease.World journal of gastroenterology · 2019Article
- Capsule endoscopy findings for the diagnosis of Crohn's disease: a nationwide case-control study.Journal of gastroenterology · 2019Article
- Diagnostic value of OMOM capsule endoscopy for small bowel diseases in adults.Experimental and therapeutic medicine · 2018Article
- Magnetic-Guided Capsule Endoscopy in the Diagnosis of Gastrointestinal Diseases in Minors.Gastroenterology research and practice · 2018Article
- Observational
- Diagnosis and management of inflammatory bowel disease in children.BMJ (Clinical research ed.) · 2017Review
- Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified.World journal of gastrointestinal endoscopy · 2017Article
- Current role of capsule endoscopy in Crohn's disease.World journal of gastrointestinal endoscopy · 2016Review
- Video capsule endoscopy in inflammatory bowel disease.World journal of gastrointestinal endoscopy · 2016Review
- Capsule Endoscopy for Crohn's Disease: Current Status of Diagnosis and Management.Gastroenterology research and practice · 2016Review
- Role of wireless capsule endoscopy in the follow-up of inflammatory bowel disease.World journal of gastrointestinal endoscopy · 2015Review
- Guidelines for video capsule endoscopy: emphasis on Crohn's disease.Clinical endoscopy · 2015Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAccurately classifying inflammatory bowel disease (IBD) type in pediatric patients may impact medical decision-making, direct therapy, and improve outcomes.
methodsThis was a prospective cohort study evaluating classification of IBD and patient management with use of capsule endoscopy in pediatric patients with suspected or known IBD. Treating physicians completed a questionnaire before and after capsule endoscopy (CE) assessing clinical suspicion of Crohn's disease (CD) diagnosis, patient management decisions, and perceived impact of CE findings.
resultsEighteen subjects [11F/7M, mean age 13.8 (± 2.5) years], 4 previously diagnosed with CD, 4 with ulcerative or indeterminate colitis (UC/IC), and 10 "suspected" to have IBD were included. Following CE, 2 of 4 (50%) UC/IC patients were reclassified as having small bowel CD. In the 4 subjects with known CD, 2 (50%) had CE evidence of more proximal small bowel mucosal disease than previously recognized. In the 10 subjects with "suspected" IBD, 8 (80%) had SB ulcerations leading to a definitive diagnosis of CD. Treating physicians reported CE helped diagnosing CD in 15 of 18 (83.3%) subjects and impacted medical decision-making in 13 of 18 (72.2%), leading to a change in medical management in 14 of 18 (77.8%).
conclusionsIn "suspected" pediatric IBD, CE often leads to a definitive diagnosis of CD. CE can lead to reclassification of IBD from UC/IC to CD and previously diagnosed CD patients may have a more significant burden of small bowel disease. These data may help integrate CE in evaluating IBD patients, lead to more targeted medical management changes and improve outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.