ArticleJournal of human hypertension2013
To dip or not to dip? The unique relationship between different blood pressure patterns and cardiac function and structure.
Article in Journal of human hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nighttime dipping status and risk of cardiovascular events in patients with untreated hypertension: A systematic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2020Pooled it
- Cardiovascular complications in children with Down syndrome and sleep disordered breathing.Paediatric respiratory reviews · 2025Review
- Association of 24-h Blood Pressure Pattern With Mortality in ICU Patients: A Multicenter Retrospective Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Observational
- Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring.Journal of clinical hypertension (Greenwich, Conn.) · 2024Observational
- Association between non-dipping blood pressure pattern and different glucometabolic profile during oral glucose tolerance test.Internal and emergency medicine · 2024Article
- Role of sympathetic pathway in light-phase time-restricted feeding-induced blood pressure circadian rhythm alteration.Frontiers in nutrition · 2022Article
- Is there any true distinction in extreme dipping versus nondipping or dipping phenotype regarding hypertension-mediated organ damage in newly diagnosed and never-treated hypertensive patients?Journal of human hypertension · 2022Article
- Cardiac Remodeling According to the Nocturnal Fall of Blood Pressure in Hypertensive Subjects: The Whole Assessment of Cardiac Abnormalities in Non-Dipper Subjects with Arterial Hypertension (Wacanda) Study.Journal of personalized medicine · 2021Article
- Extreme dipping and target organ damage: is there any relationship?Journal of human hypertension · 2021Article
- Characteristics of Circadian Blood Pressure Pattern of Hypertensive Patients According to Localization of Fragmented QRS on Electrocardiography.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Do reverse dippers have the highest risk of right ventricular remodeling?Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Nocturnal blood pressure patterns and cardiac damage: there is still much to learn.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- QTc Interval Predicts Disturbed Circadian Blood Pressure Variation.Open medicine (Warsaw, Poland) · 2020Article
- The Prognostic Effect of Circadian Blood Pressure Pattern on Long-Term Cardiovascular Outcome is Independent of Left Ventricular Remodeling.Journal of clinical medicine · 2019Article
- Influence of circadian blood pressure patterns and cardiopulmonary functional capacity in hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Noctural dipping status and left ventricular hypertrophy: A cardiac magnetic resonance imaging study.Journal of clinical hypertension (Greenwich, Conn.) · 2018Observational
- Right heart remodeling induced by arterial hypertension: Could strain assessment be helpful?Journal of clinical hypertension (Greenwich, Conn.) · 2018Review
- Assessment of left atrial function: Another window to detect early cardiac impairment?Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Clinical and prognostic significance of a reverse dipping pattern on ambulatory monitoring: An updated review.Journal of clinical hypertension (Greenwich, Conn.) · 2017Review
- Associations of Blood Pressure Dipping Patterns With Left Ventricular Mass and Left Ventricular Hypertrophy in Blacks: The Jackson Heart Study.Journal of the American Heart Association · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dipping and nondipping blood pressure (BP) patterns are associated with different levels of target organ damage and cardiovascular risk. The aim of our investigation was to determine the relationship between different BP patterns (dipping, nondipping, extreme dipping and reverse dipping type) and cardiac structure, and function in hypertensive patients. This cross-sectional study included 376 hypertensive patients. All subjects underwent 24-h ambulatory BP monitoring, and complete two-dimensional, pulsed and tissue Doppler echocardiography. Most of the parameters of the left ventricular (LV) diastolic function (E/A, e'/a', E/e') significantly and progressively deteriorated from the extreme dippers to the dippers and nondippers, and finally to the reverse dippers. In contrast, LV structural parameters (IVS, RWT, LV mass index) showed a statistically important difference only by comparing the dippers and the extreme dippers with the rest of the patients. Simultaneously, the right ventricular (RV) structural parameter (RVT, right ventricular thickness), and most RV diastolic parameters significantly and progressively worsened from the extreme dippers, over the dippers and the nondippers, to the reverse dippers. Daytime and night time systolic BP, nocturnal systolic BP fall, and the nondipping and the reverse dipping status were independently associated with LV and RV structure, as well as with diastolic function. LV and RV structure, and diastolic function were significantly more impaired with the nondippers and the reverse dippers compared with others.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.