ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Carbon nanotube scaffolds tune synaptic strength in cultured neural circuits: novel frontiers in nanomaterial-tissue interactions.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Advances in methotrexate nano-formulations to enhance therapeutic efficacy against drug-resistant breast cancer.Discover nano · 2026Review
- What Is New in Spinal Cord Injury Management: A Narrative Review on the Emerging Role of Nanotechnology.Biomedicines · 2025Review
- Review
- Interface-Mediated Neurogenic Signaling: The Impact of Surface Geometry and Chemistry on Neural Cell Behavior for Regenerative and Brain-Machine Interfacing Applications.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Graphene-Related Nanomaterials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2023Review
- Advances in Conductive Hydrogel for Spinal Cord Injury Repair and Regeneration.International journal of nanomedicine · 2023Review
- Bonding of Neuropeptide Y on Graphene Oxide for Drug Delivery Applications to the Central Nervous System.ACS applied nano materials · 2022Article
- Receptor-targeting nanomaterials alleviate binge drinking-induced neurodegeneration as artificial neurotrophins.Exploration (Beijing, China) · 2021Article
- Dielectric Elastomer Actuators, Neuromuscular Interfaces, and Foreign Body Response in Artificial Neuromuscular Prostheses: A Review of the Literature for an In Vivo Application.Advanced healthcare materials · 2021Review
- Nanotechnology Facilitated Cultured Neuronal Network and Its Applications.International journal of molecular sciences · 2021Review
- Review
- Distribution in the brain and possible neuroprotective effects of intranasally delivered multi-walled carbon nanotubes.Nanoscale advances · 2021Article
- Bidirectional Modulation of Neuronal Cells Electrical and Mechanical Properties Through Pristine and Functionalized Graphene Substrates.Frontiers in neuroscience · 2021Article
- Functional rewiring across spinal injuries via biomimetic nanofiber scaffolds.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- 3D-printed scaffolds with carbon nanotubes for bone tissue engineering: Fast and homogeneous one-step functionalization.Acta biomaterialia · 2020Article
- Nano-porous anodic alumina: fundamentals and applications in tissue engineering.Journal of materials science. Materials in medicine · 2020Review
- BDNF impact on synaptic dynamics: extra or intracellular long-term release differently regulates cultured hippocampal synapses.Molecular brain · 2020Article
- Mechanotransduction in neuronal cell development and functioning.Biophysical reviews · 2019Review
- Interactions of Functionalized Multi-Wall Carbon Nanotubes with Giant Phospholipid Vesicles as Model Cellular Membrane System.Scientific reports · 2018Article
- Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications.Polymers · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A long-term goal of tissue engineering is to exploit the ability of supporting materials to govern cell-specific behaviors. Instructive scaffolds code such information by modulating (via their physical and chemical features) the interface between cells and materials at the nanoscale. In modern neuroscience, therapeutic regenerative strategies (i.e., brain repair after damage) aim to guide and enhance the intrinsic capacity of the brain to reorganize by promoting plasticity mechanisms in a controlled fashion. Direct and specific interactions between synthetic materials and biological cell membranes may play a central role in this process. Here, we investigate the role of the material's properties alone, in carbon nanotube scaffolds, in constructing the functional building blocks of neural circuits: the synapses. Using electrophysiological recordings and rat cultured neural networks, we describe the ability of a nanoscaled material to promote the formation of synaptic contacts and to modulate their plasticity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.