Evidence map›Paper›PMID 21900487›Full record

ArticleThe Journal of infectious diseases2011

Prevalence of toscana and sicilian phlebovirus antibodies in classic Kaposi sarcoma case patients and control subjects in sicily.

Emanuele Amodio, Melissa Valentini, Gianni Gori-Savellini, Rosalia Maria Valenti, Nino Romano, James J Goedert, Maria Grazia Cusi

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Immunoglobulin M seropositivity for Toscana virus in a random population sample in Sicily.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2012
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emanuele AmodioDepartment of Sciences for Health Promotion G. D'Alessandro, University of Palermo, Italy.
Melissa Valentini
Gianni Gori-Savellini
Rosalia Maria Valenti
Nino Romano
James J Goedert
Maria Grazia Cusi

Funding

Microbes and Human MalignanciesZIACP010214 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI VOGTMANN, EMILY · 2010 to 2021
$5.5M
Intramural NIH HHS
6 · The paper itself

Abstract

To assess whether arthropod bites promote Kaposi sarcoma (KS), we determined the seroprevalence of Sicilian (SFSV) and Toscana (TOSV) phlebovirus antibodies in 30 patients with classic KS and 100 controls in Sicily. Nine (6.9%) subjects, all controls, were positive for SFSV, whereas 41 (31.5%) were positive for TOSV. Seroprevalence with immunoglobulin (Ig) M or IgG against either virus was significantly higher in controls (43% vs 13.3% in case patients; P < .01). Adjusted for age, IgG seroprevalence was significantly lower in KS patients compared to controls (adjusted odds ratio, 0.22; 95% confidence interval, .07-.72). Low phlebovirus seroprevalence in patients with KS may reflect incapacity to produce robust, persistent antibody responses, and suggests that arthropod bites do not promote KS.

Indexed as

AgedAged, 80 and overAntibodies, ViralComorbidityFemaleHerpesvirus 8, HumanHumansImmunoglobulin GImmunoglobulin MItalyMaleMiddle AgedPhlebovirusSarcoma, KaposiSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GImmunoglobulin M

Identifiers

PMID21900487
PMCPMC3182312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.