Folate consumption and cancer risk: a confirmation and some reassurance, but we're not out of the woods quite yet.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Folate and global health umbrella review series, part 2: syntheses on cancers.Journal of global health · 2026
   Pooled it
2. Folate intake and the risk of endometrial cancer: A meta-analysis.Oncotarget · 2016
   Pooled it
3. Folate-Associated DNA Methylation and Chemotherapy-Induced Toxicities in Patients With Colorectal Cancer.Molecular nutrition & food research · 2025
   Review
4. Biological, dietetic and pharmacological properties of vitamin BNPJ science of food · 2025
   Review
5. Presence of circulating folic acid in plasma and its relation with dietary intake, vitamin B complex concentrations and genetic variants.European journal of nutrition · 2019
   Article
6. Safety of folic acid.Annals of the New York Academy of Sciences · 2018
   Review
7. An overview of folate status in a population-based study from São Paulo, Brazil and the potential impact of 10 years of national folic acid fortification policy.European journal of clinical nutrition · 2017
   Article
8. Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing.Nutrients · 2016
   Review
9. One-carbon metabolism dietary factors and distal gastric cancer risk in chinese women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
   Article

Corrections and comments

• Comment on
  Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States.2011

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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