ArticleGenesis (New York, N.Y. : 2000)2012
Mouse transgenic lines that selectively label Type I, Type IIA, and Types IIX+B skeletal muscle fibers.
Article in Genesis (New York, N.Y. : 2000), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Creation of knockin mice for the fluorescence protein based in vivo identification of skeletal myofiber types.Scientific reports · 2025Article
- Effects of 3-(4-Hydroxy-3-methoxyphenyl)propionic Acid on Regulating Oxidative Stress and Muscle Fiber Composition.Nutrients · 2025Article
- Myokine BDNF highly expressed in Type I fibers inhibits the differentiation of myotubes into Type II fibers.Molecular biology reports · 2024Article
- A neural algorithm for computing bipartite matchings.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Normal muscle fiber type distribution is recapitulated in aged ephrin-A3American journal of physiology. Cell physiology · 2023Article
- R-spondin3 is a myokine that differentiates myoblasts to type I fibres.Scientific reports · 2022Article
- Assessment the effect of genomic selection and detection of selective signature in broilers.Poultry science · 2022Article
- Critical Limb Ischemia Induces Remodeling of Skeletal Muscle Motor Unit, Myonuclear-, and Mitochondrial-Domains.Scientific reports · 2019Article
- Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution.Development (Cambridge, England) · 2018Article
- Impact of Aging on Proprioceptive Sensory Neurons and Intrafusal Muscle Fibers in Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2017Article
- Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle.Cell reports · 2016Article
- Peripheral optogenetic stimulation induces whisker movement and sensory perception in head-fixed mice.eLife · 2016Article
- Nerve Growth Factor Promotes Angiogenesis and Skeletal Muscle Fiber Remodeling in a Murine Model of Hindlimb Ischemia.Chinese medical journal · 2016Article
- VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions.Skeletal muscle · 2016Article
- Ephrin-A3 promotes and maintains slow muscle fiber identity during postnatal development and reinnervation.The Journal of cell biology · 2015Article
- Mitochondrial Dynamics is a Distinguishing Feature of Skeletal Muscle Fiber Types and Regulates Organellar Compartmentalization.Cell metabolism · 2015Article
- Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions.eLife · 2015Article
- Heterogeneous activation of a slow myosin gene in proliferating myoblasts and differentiated single myofibers.Developmental biology · 2015Article
- Article
- Characterization of early pathogenesis in the SOD1(G93A) mouse model of ALS: part II, results and discussion.Brain and behavior · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Skeletal muscle fibers vary in contractile and metabolic properties. Four main fiber types are present in mammalian trunk and limb muscles; they are called I, IIA, IIX, and IIB, ranging from slowest- to fastest-contracting. Individual muscles contain stereotyped proportions of two or more fiber types. Fiber type is determined by a combination of nerve-dependent and -independent influences, leading to formation of "homogeneous motor units" in which all branches of a single motor neuron form synapses on fibers of a single type. Fiber type composition of muscles can be altered in adulthood by multiple factors including exercise, denervation, hormones, and aging. To facilitate analysis of muscle development, plasticity, and innervation, we generated transgenic mouse lines in which Type I, Type IIA, and Type IIX+B fibers can be selectively labeled with distinguishable fluorophores. We demonstrate their use for motor unit reconstruction and live imaging of nerve-dependent alterations in fiber type.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.