ArticlePloS one2011
Spiking patterns and their functional implications in the antennal lobe of the tobacco hornworm Manduca sexta.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Neuron synchronization analyzed through spatial-temporal attention.Frontiers in computational neuroscience · 2025Article
- Combinatorial encoding of odors in the mosquito antennal lobe.Nature communications · 2023Article
- Experimental and theoretical probe on mechano- and chemosensory integration in the insect antennal lobe.Frontiers in physiology · 2022Article
- Effects of Mechanosensory Input on the Tracking of Pulsatile Odor Stimuli by Moth Antennal Lobe Neurons.Frontiers in neuroscience · 2021Article
- Effect of interpopulation spike-timing-dependent plasticity on synchronized rhythms in neuronal networks with inhibitory and excitatory populations.Cognitive neurodynamics · 2020Article
- Flight motor networks modulate primary olfactory processing in the mothProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Overexpression of cypin alters dendrite morphology, single neuron activity, and network properties via distinct mechanisms.Journal of neural engineering · 2018Article
- Biological Mechanisms for Learning: A Computational Model of Olfactory Learning in theFrontiers in computational neuroscience · 2018Article
- Intrinsic and Network Mechanisms Constrain Neural Synchrony in the Moth Antennal Lobe.Frontiers in physiology · 2016Article
- Three floral volatiles contribute to differential pollinator attraction in monkeyflowers (Mimulus).The Journal of experimental biology · 2014Article
- Data-driven inference of network connectivity for modeling the dynamics of neural codes in the insect antennal lobe.Frontiers in computational neuroscience · 2014Article
- Synchronous firing of antennal-lobe projection neurons encodes the behaviorally effective ratio of sex-pheromone components in male Manduca sexta.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Article
- Identification of olfactory volatiles using gas chromatography-multi-unit recordings (GCMR) in the insect antennal lobe.Journal of visualized experiments : JoVE · 2013Article
- Machine learning for automatic prediction of the quality of electrophysiological recordings.PloS one · 2013Article
- Antennal lobe processing correlates to moth olfactory behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Nitric oxide has differential effects on currents in different subsets of Manduca sexta antennal lobe neurons.PloS one · 2012Article
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Authors and funding
5 authors.
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Abstract
Bursting as well as tonic firing patterns have been described in various sensory systems. In the olfactory system, spontaneous bursts have been observed in neurons distributed across several synaptic levels, from the periphery, to the olfactory bulb (OB) and to the olfactory cortex. Several in vitro studies indicate that spontaneous firing patterns may be viewed as "fingerprints" of different types of neurons that exhibit distinct functions in the OB. It is still not known, however, if and how neuronal burstiness is correlated with the coding of natural olfactory stimuli. We thus conducted an in vivo study to probe this question in the OB equivalent structure of insects, the antennal lobe (AL) of the tobacco hornworm Manduca sexta. We found that in the moth's AL, both projection (output) neurons (PNs) and local interneurons (LNs) are spontaneously active, but PNs tend to produce spike bursts while LNs fire more regularly. In addition, we found that the burstiness of PNs is correlated with the strength of their responses to odor stimulation--the more bursting the stronger their responses to odors. Moreover, the burstiness of PNs was also positively correlated with the spontaneous firing rate of these neurons, and pharmacological reduction of bursting resulted in a decrease of the neurons' responsiveness. These results suggest that neuronal burstiness reflects a physiological state of these neurons that is directly linked to their response characteristics.
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