ArticleInternational journal of Ayurveda research2011
Blood compatibility studies of Swarna bhasma (gold bhasma), an Ayurvedic drug.
Article in International journal of Ayurveda research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 74 citations in OpenAlex.
- New Approaches in Breast Cancer Therapy Through Green Nanotechnology and Nano-Ayurvedic Medicine - Pre-Clinical and Pilot Human Clinical Investigations.International journal of nanomedicine · 2020Trial
- Effectiveness of combinations of Ayurvedic drugs in alleviating drug toxicity and improving quality of life of cancer patients treated with chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014Trial
- Characterization of Swarna Bhasma and Swarnaprash and Determination of Antimicrobial Properties Against Gut-Pathobiont and Symbiont.Biological trace element research · 2025Article
- Advancements in Nano-Mandoor Bhasma: Unravelling the Particle Size-Ascorbic Acid Synergy for Enhanced Iron Bioavailability for Anemia Treatment.Biological trace element research · 2025Article
- Integrated management of diabetic foot ulcers (DFU) using a smartphone - A case report.International journal of surgery case reports · 2024Article
- Investigating the Role of Classical Ayurveda-Based Incineration Process on the Synthesis of Zinc Oxide Based Jasada Bhasma Nanoparticles and ZnACS omega · 2023Article
- Nanoscale Diamond-Based Formulation as an Immunomodulator and Potential Therapeutic for Lymphoma.Frontiers in pharmacology · 2022Article
- Swarna Bindu Prashana-an Ancient Approach to Improve the Infant's Immunity.Biological trace element research · 2021Review
- Role of gold nanoparticles in advanced biomedical applications.Nanoscale advances · 2020Review
- Adverse events with ayurvedic medicines- possible adulteration and some inherent toxicities.Wellcome open research · 2019Article
- Intracellular Synthesis of Gold Nanoparticles Using an Ectomycorrhizal Strain EM-1083 ofIndian journal of microbiology · 2017Article
- Comparative study on cellular entry of incinerated ancient gold particles (Swarna Bhasma) and chemically synthesized gold particles.Scientific reports · 2017Article
- Protection against osteoarthritis in experimental animals by nanogold conjugated snake venom protein toxin gold nanoparticle-The Indian journal of medical research · 2016Article
- Toxicity Evaluation of Pũrṇa Cantirotaya Centũram, a Siddha Medicine in Wistar Rats.International scholarly research notices · 2015Article
- Bhasma : The ancient Indian nanomedicine.Journal of advanced pharmaceutical technology & research · 2014Review
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- Steven-Johnson syndrome may NOT be due to ayurvedic drugs - 1.Indian journal of pharmacology · 2012Article
- Nanostructured gold in ancient Ayurvedic calcined drug 'swarnabhasma'.Journal of Ayurveda and integrative medicineArticle
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Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Swarna bhasma (gold bhasma) preparations are widely utilized as therapeutic agents. However, in vitro biological evaluations of bhasma preparations are needed along with the physicochemical characterization for present day standardization of metallic bhasma preparations to meet the criteria that supports its use. Therefore, an attempt has been made to evaluate the protein adsorption, blood compatibility and complement activation potential of two batches of Swarna bhasma preparation, along with its physicochemical characterization. The particle size, morphology, elemental analysis, and in vitro cytotoxicity were evaluated initially. Red blood cell hemolysis, aggregation studies with blood cells, protein adsorption, complement C3 adsorption, platelet activation and tight junction permeability in Caco-2 cell line were investigated. The Swarna bhasma preparations with a crystallite size of 28-35 nm did not induce any blood cell aggregation or protein adsorption. Activation potential of these preparations towards complement system or platelets was negligible. These particles were also non-cytotoxic. Swarna bhasma particles opened the tight junctions in Caco-2 cell experiments. The results suggest the application of Swarna bhasma preparations as a therapeutic agent in clinical medicine from the biological safety point of view.
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