Evidence map›Paper›PMID 21897452›Full record

ArticleBMJ case reports2011

A 7-year-old with pulmonary hypertension.

James Olin, Steven Abman, R Grady, D Ivy, Mark Lovell, David Partrick, Vivek Balasubramaniam

Open access · greenAbstract read
In one paragraph

Article in BMJ case reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

James OlinDepartment of Pediatrics, University of Colorado, Aurora, Colorado, USA.
Steven Abman
R Grady
D Ivy
Mark Lovell
David Partrick
Vivek Balasubramaniam
University of Colorado Denver · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Boulder · USWashington University in St. Louis · US

Funding

Non-Invasive Inhaled NO in Premature NewbornsP50HL084923 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 2007 to 2012
$11.2M
NHLBI NIH HHS P50 HL084923
6 · The paper itself

Abstract

The authors discuss the case of a 7-year-old female who presented with exertional cyanosis and was found to have pulmonary arterial hypertension. Despite normal left-sided heart function, the patient developed pulmonary oedema in response to pulmonary vasodilator therapy, increasing suspicion for pathology in the pulmonary capillaries and veins. Lung biopsy confirmed a diagnosis of pulmonary capillary haemangiomatosis (PCH), a rare cause of pulmonary hypertension in both children and adults. The diagnosis requires lung biopsy and is often made postmortem. She was treated with interferon α-2a and doxycycline for their antiangiogenic properties and reports of disease regression. Although she initially demonstrated improvement in her pulmonary hypertension in response to these medications, she succumbed to the disease within the time frame previously reported for PCH.

Identifiers

PMID21897452
PMCPMC3082056
OpenAlexW1970577863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.