ArticleNature communications2011
Microfluidic quadrupole and floating concentration gradient.
Article in Nature communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Streaming-based Tweezers for Routing, Engineering, and Manipulation of multiparticles: STREAM.Microsystems & nanoengineering · 2025Article
- Proof of concept for brain organoid-on-a-chip to create multiple domains in forebrain organoids.RSC advances · 2025Article
- Microfluidic mixing probe: generating multiple concentration-varying flow dipoles.Scientific reports · 2025Article
- Open-Top Patterned Hydrogel-Laden 3D Glioma Cell Cultures for Creation of Dynamic Chemotactic Gradients to Direct Cell Migration.ACS biomaterials science & engineering · 2024Article
- The vascular geometry of the choriocapillaris is associated with spatially heterogeneous molecular exchange with the outer retina.The Journal of physiology · 2024Article
- Pixelated Microfluidics for Drug Screening on Tumour Spheroids and Ex Vivo Microdissected Tumour Explants.Cancers · 2023Article
- Microenvironmental Analysis and Control for Local Cells under Confluent Conditions via a Capillary-Based Microfluidic Device.Analytical chemistry · 2022Article
- Circuit-Based Design of Microfluidic Drop Networks.Micromachines · 2022Review
- Pixel-based open-space microfluidics for versatile surface processing.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Grayscale surface patterning using electrophoretic motion through a heterogeneous hydrogel material.Electrophoresis · 2020Article
- Spatial presentation of biological molecules to cells by localized diffusive transfer.Lab on a chip · 2019Article
- Microfluidic multipoles theory and applications.Nature communications · 2019Article
- Chemical operations on a living single cell by open microfluidics for wound repair studies and organelle transport analysis.Chemical science · 2019Article
- Digital acoustofluidics enables contactless and programmable liquid handling.Nature communications · 2018Article
- 3D Printed Microfluidic Probes.Scientific reports · 2018Article
- Form, shape and function: segmented blood flow in the choriocapillaris.Scientific reports · 2016Article
- Rapid Subtractive Patterning of Live Cell Layers with a Microfluidic Probe.Journal of visualized experiments : JoVE · 2016Article
- Selective local lysis and sampling of live cells for nucleic acid analysis using a microfluidic probe.Scientific reports · 2016Article
- Two-Aperture Microfluidic Probes as Flow Dipole: Theory and Applications.Scientific reports · 2015Article
- A neutrophil treadmill to decouple spatial and temporal signals during chemotaxis.Lab on a chip · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The concept of fluidic multipoles, in analogy to electrostatics, has long been known as a particular class of solutions of the Navier-Stokes equation in potential flows; however, experimental observations of fluidic multipoles and of their characteristics have not been reported yet. Here we present a two-dimensional microfluidic quadrupole and a theoretical analysis consistent with the experimental observations. The microfluidic quadrupole was formed by simultaneously injecting and aspirating fluids from two pairs of opposing apertures in a narrow gap formed between a microfluidic probe and a substrate. A stagnation point was formed at the centre of the microfluidic quadrupole, and its position could be rapidly adjusted hydrodynamically. Following the injection of a solute through one of the poles, a stationary, tunable, and movable-that is, 'floating'-concentration gradient was formed at the stagnation point. Our results lay the foundation for future combined experimental and theoretical exploration of microfluidic planar multipoles including convective-diffusive phenomena.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.