Evidence map›Paper›PMID 21896680›Full record

ReviewmBio2011

Antimicrobial actions of reactive oxygen species.

Ferric C Fang

Open access · goldAbstract readReview
In one paragraph

Review in mBio, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 370 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Linking the production of reactive oxygen species to the expression of antimicrobial peptides through aquaporin in an arthropod.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ferric C FangDepartment of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle, Washington, USA. fcfang@u.washington.edu
University of Washington · US

Funding

THE SALMONELLA TYPHIMURIUM SIGMAE REGULONR01AI044486 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 1999 to 2016
$4.9M
NITRIC OXIDE CYTOTOXICITY IN SALMONELLOSISR01AI039557 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 1997 to 2012
$4.1M
Iron Homeostasis in Salmonella-Host InteractionsR01AI077629 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2009 to 2010
$780k
A Humanized Mouse Model of Typhoid FeverR21AI091966 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2011 to 2012
$429k
MECHANISMS OF NITRIC OXIDE CYTOTOXICITY IN SALMONELLOSISR21AI039557 · NIAID · UNIVERSITY OF COLORADO DENVER · PI FANG, FERRIC C · 1996 to 1996
–
NIAID NIH HHS AI39557NIAID NIH HHS AI44486NIAID NIH HHS AI77629NIAID NIH HHS AI91966NIAID NIH HHS R01 AI039557NIAID NIH HHS R01 AI044486NIAID NIH HHS R01 AI077629NIAID NIH HHS R21 AI091966
6 · The paper itself

Abstract

Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.

Indexed as

Anti-Bacterial AgentsHost-Pathogen InteractionsPhagocytesReactive Oxygen SpeciesSalmonellaAnti-Bacterial AgentsReactive Oxygen Species

Identifiers

PMID21896680
PMCPMC3171981
OpenAlexW2165985796

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.