Evidence map›Paper›PMID 21896560›Full record

ArticleHuman reproduction update

Contemporary genetic technologies and female reproduction.

Evian Annual Reproduction (EVAR) Workshop Group 2010, B C J M Fauser, K Diedrich, P Bouchard, F Domínguez, M Matzuk, S Franks, S Hamamah, C Simón, P Devroey and 2 more

Erratum issuedOpen access · bronzeAbstract readConference Proceedings
In one paragraph

Article in Human reproduction update. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 348 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Integrative Analysis Reveals Regulatory Programs in Endometriosis.Reproductive sciences (Thousand Oaks, Calif.) · 2015
    Article
  10. Review
  11. Article
  12. Promise(s) of using mesenchymal stem cells in reproductive disorders.The Indian journal of medical research · 2014
    Review
  13. Article
  14. The complementary and alternative medicine for endometriosis: a review of utilization and mechanism.Evidence-based complementary and alternative medicine : eCAM · 2014
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

12 authors.

Evian Annual Reproduction (EVAR) Workshop Group 2010
B C J M Fauser
K Diedrich
P Bouchard
F Domínguez
M Matzuk
S Franks
S Hamamah
C Simón
P Devroey
D Ezcurra
C M Howles

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction.

methodsSpecialist reproductive medicine clinicians and geneticists delivered presentations based on published literature and current research. The content of this report is based on the expert presentations and subsequent group discussions that took place during this Workshop.

resultsNumerous ovarian genes with a role in infertility have been identified. Future challenges for genetic screening of patients, such as those with polycystic ovary syndrome, primary ovarian insufficiency or endometriosis, include the identification of high-throughput strategies and how to apply these findings to infertile patients. The identification of high-quality embryos in IVF using objective technologies remains a high priority in order to facilitate single-embryo transfer. Gene expression profiling of cumulus cells surrounding the oocyte, and proteomic and metabolomic approaches in embryo culture media may significantly improve non-invasive embryo quality assessment.

conclusionsThe way forward in advancing the knowledge of genes involved in reproduction was considered to be through genome-wide association studies involving large numbers of patients. Establishing international collaboration is required to enable the application of such technologies in sufficient numbers of patients.

Indexed as

Embryonic DevelopmentEndometriosisFemaleGenetic TechniquesHumansModels, GeneticMutationOocytesOvaryPolycystic Ovary SyndromePregnancyPrimary Ovarian InsufficiencyReproductionReproductive Techniques, Assisted

Identifiers

PMID21896560
PMCPMC3191938
OpenAlexW2120078601

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.